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UrduThe discovery of the oncogene responsible for glioblastoma could be the brain tumor’s Achilles’ heel, one researcher says.
Tag: Glioblastoma
Focused ultrasound shows promise against deadliest brain tumor
An innovative use of focused ultrasound is showing promise against glioblastoma, the deadliest brain tumor, and could prove useful against other difficult-to-treat cancers.
Treatment shows promise in treating deadly brain cancer
In this study, researchers investigated if specific targeting of CD133+ glioblastoma with cutting-edge immunotherapy drugs could eradicate the most aggressive subpopulation of cells in the tumour. They also looked at the safety of CD133-targeting therapies on normal, non-cancerous human stem cells including hematopoietic stem cells which create blood cells and progenitor cells which can form one or more kinds of cells.
Targeting Stromal Cells May Help Overcome Treatment Resistance in Glioblastoma
The deadly brain cancer glioblastoma (GBM) is often resistant to chemotherapy and radiation, but new research shows targeting stromal cells – the cells that serve as the connective tissue of the organs – may be an effective way of overcoming that resistance
Stem Cells, CRISPR and Gene Sequencing Technology are Basis of New Brain Cancer Model
University of California San Diego School of Medicine researchers created a new type of brain cancer model for glioblastoma using stem cells, CRISPR and gene sequencing.
A Menu of Brain Cancer Treatments
Sara Piccirillo, PhD, is passionate about finding a way to beat glioblastoma, the most aggressive type of brain cancer. Her research focuses on a feature of glioblastoma tumors that appears to be the source of their strength: the extreme differences among their tumor cells.
International Research Team Confirms Potential Glioblastoma Inhibitors
However, San Diego Supercomputer Center (SDSC) Research Scientist Igor Tsigelny recently collaborated Researchers from the San Diego Supercomputer at UC San Diego and colleagues from Sweden’s Karolinska Institute and the Pasteur Institute in France released a study focused on improving the prognosis for glioblastoma patients.
Zika Virus’ Key into Brain Cells ID’d, Leveraged to Block Infection and Kill Cancer Cells
Two different UC San Diego research teams identified the same molecule — αvβ5 integrin — as Zika virus’ key to brain cell entry. They found ways to take advantage of the integrin to both block Zika virus from infecting cells and turn it into something good: a way to shrink brain cancer stem cells.
Surgery May Add Months or Years of Survival For Adults With Rare And Deadly Brain Cancers
For adult patients with brainstem high-grade gliomas — one of the rarest and deadliest forms of brain cancer — surgically removing the entire tumor may add many months or potentially years of survival beyond that offered by radiation and chemotherapy, according to results of a medical records study led by researchers at the Johns Hopkins Kimmel Cancer Center.
Brain Organoids Reveal Glioblastoma Origins
Glioblastomas are the most aggressive form of brain cancer – they grow and spread rapidly through the brain and are virtually impossible to eradicate, typically leading to death within one or two years of diagnosis. Scientists are constantly seeking more powerful targeted therapies, but so far without success — in part because glioblastomas are challenging to study in a laboratory setting.
Researchers identify immune-suppressing target in glioblastoma
Researchers at The University of Texas MD Anderson Cancer Center have identified a tenacious subset of immune macrophages that thwart treatment of glioblastoma with anti-PD-1 checkpoint blockade, elevating a new potential target for treating the almost uniformly lethal brain tumor.
A Cancer Drug Trial For Dogs Presented At The RSNA Annual Meeting
What do you do when your best friend is diagnosed with a cancer that kills most of its patients within a few months? A few brave dog owners turned to Johns Hopkins, where veterinarians, radiologists and physicists have teamed up to conduct an experimental trial of a therapy they hope will extend the lives of their beloved pets.
Blood Test Can Predict Prognosis in Deadly Brain Cancer
A blood test that measures the amount of cell-free DNA (cfDNA) in the bloodstream – called a liquid biopsy – correlates with how patients will progress after they are diagnosed with glioblastoma (GBM), the deadliest and most common primary brain tumor in adults
Tulane University student spends summer conducting brain tumor research in Switzerland
Tulane University senior James Rogers has been charting a course in the name of research since he arrived on campus in the fall of 2016. Rogers’ journey has led him from New Orleans to Bethesda, Md., across the Atlantic to Scotland and, most recently, Switzerland, where he spent the summer as a visiting research scholar in the Brain Tumor Center at the University Hospital Zürich (USZ).
Delivering Immunotherapy Directly to Brain Tumors
A new study published this week gives insight into how cancer immunotherapies might one day be delivered directly to the brain in order to treat brain tumors.
Adding MS Drug to Targeted Cancer Therapy May Improve Glioblastoma Outcomes
The multiple sclerosis drug teriflunomide, paired with targeted cancer therapy, markedly shrinks patient-derived glioblastomas grown in mice by reaching stem cells at the tumor’s root, according to a new UC San Diego School of Medicine study published in Science Translational Medicine.