Why We Want to Drink, What That Has to Do with Genes, and Why it Matters for Our Alcohol Risk

Motives for drinking — to party, to conform, to cope, or to feel good — are consistent through young adulthood, and genes play a role in how those motives influence alcohol use, a new study of college students suggests. Understanding the mechanisms linking genetic variants to differences in drinking behaviors could present opportunities for predicting individuals’ vulnerability to Alcohol Use Disorder (AUD) and intervening to prevent it. Genetic factors are responsible for about 50% of individual risk of AUD. Much of how that heritability functions is unexplained, however. The relationship between genes and drinking behavior is complex, involving thousands of genetic variants that each have small effects. Critical factors known as endophenotypes, or intermediary phenotypes, affect how an individual’s genetic predisposition manifests as a behavioral trait. For the new study in Alcoholism: Clinical & Environmental Research, investigators sought to determine whether drinking motives are o

In the Mood for Drinking? Study Tracks College Students’ Emotion Dynamics During Drinking and Non-drinking Days

A study reported in Alcoholism: Clinical and Experimental Research has highlighted the link between emotional functioning and alcohol use. Previous research has shown that mood regulation is a core component of problematic drinking, and that emotions have a role in reinforcing repeated alcohol use – whether via the mood- and social-enhancing effects of alcohol (‘positive reinforcement’), or through drinking as a coping strategy to alleviate negative feelings of stress and anxiety (‘negative reinforcement’). According to theoretical models of addiction, alcohol reinforcement can act as a pathway to development of alcohol misuse and dependence over the longer-term. However, it is also important to understand the daily impact of emotional regulation and alcohol associations. In the latest study, researchers from the University of Central Florida examined snapshots of mood in college students in real time across drinking and non-drinking days, using a technique called ecological momentary