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UrduNew research presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (Copenhagen, 15-18 April) and published in The Lancet Public Health shows that the impact of COVID-19 on mortality in people living with intellectual disabilities extended beyond deaths from the virus itself, and was linked with increased mortality in several other conditions.
Tag: COVID-19
Higher dose corticosteroids associated with a 60% increased risk of death in hypoxic COVID-19 patients requiring only non-invasive oxygen therapy
A new study to be presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2023, Copenhagen 15-18 April), and published in The Lancet, shows that, compared with standard care that included low dose corticosteroid use, treating hypoxic COVID-19 patients needing only oxygen therapy or no breathing support with higher dose corticosteroids is associated with a 60% increased risk of death.
Study: Cancer database’s cases drop 14% in pandemic’s first year, indicating 200,000 ‘missing cases’
A study, based on reported cases of new cancer diagnosis to the National Cancer Database (NCDB), estimates roughly 200,000 people with cancer cases weren’t diagnosed or treated at Commission on Cancer-accredited facilities at the onset of the pandemic in 2020, around the same time that triage guidelines recommended delays in cancer-related care.
UT Southwestern nephrologist addresses National Kidney Foundation
Susan Hedayati, M.D., Director of Clinical and Population Health Research in Nephrology at UT Southwestern, has spent a career investigating the links between kidney disease and depression and developing methods to improve care from a patient-centric perspective for those with chronic kidney disease.
COVID-19 Pandemic Will Disrupt Cancer Reporting for Years to Come
American College of Surgeons research published in JAMA Surgery reveals the complexities and variations that occurred in cancer reporting in the National Cancer Database (NCDB) because of the pandemic.
VUMC-Led Trial Shows Two Investigational Drugs Are Ineffective for Treating Severe COVID-19
A study published April 11 in the Journal of the American Medical Association (JAMA) evaluated two drugs that act on the renin-angiotensin system (RAS) as potential treatments for severe COVID-19. Severe acute respiratory syndrome coronavirus2 (SARS-CoV-2), the virus that causes COVID-19, enters pulmonary and myocardial cells through binding of its spike protein to the human angiotensin-converting enzyme 2 (ACE2). ACE2 is a vital enzyme that controls blood pressure and blood flow to multiple organs, including the lungs, heart and kidneys.
Cleveland Clinic Researchers Find Sleep Disturbances Prevalent in Long COVID
Cleveland Clinic researchers found 41% of patients with long COVID, had moderate to severe sleep disturbances. The retrospective analysis also identified risk factors for moderate to severe sleep disturbances, including race, hospitalization for COVID-19, greater anxiety severity and fatigue. After adjusting for demographics, Black patients were three times more likely to develop these sleep disturbances. The findings were published in Journal of General Internal Medicine.
Air pollution is linked to lower COVID-19 vaccine responses
People exposed to higher levels of air pollution before the pandemic had lower antibody responses to COVID-19 vaccines, according to a study led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by “la Caixa” Foundation, in collaboration with the Germans Trias i Pujol Research Institute (IGTP).
Childhood Asthma Declines During COVID-19 Pandemic
Half as many children in the United States were diagnosed with asthma in the first year of the COVID-19 pandemic compared to previous years, and Rutgers researchers think fewer colds may be part of the reason.
Asthma management post COVID: What are the challenge and opportunities?
The COVID-19 pandemic has transformed the healthcare landscape and presented new challenges for individuals and healthcare providers.
Dangerous Hitchhikers: Visualizing How We Spread Coronavirus within Our Homes
While COVID-19 can be transmitted via contact with contaminated objects, most studies have focused on airborne droplet transmission.
Largest US state-by-state analysis of COVID-19 impact reveals the driving forces behind variations in health, education, and economic performance
Four-fold variation in standardised COVID-19 death rates across US states between January 2020 and July 2022 – with death rates lowest in Hawaii, New Hampshire, and Maine and highest in Arizona, Washington, DC, and New Mexico.
A nasal spray protects against coronavirus infection – Effective also against recent immune-evasive variants
Researchers have developed a molecule that is, when administered nasally, extremely effective in preventing the disease caused by all known variants of the SARS-CoV-2 virus.
New survey finds COVID-19 pandemic changed public’s view of obesity
Nearly a third of Americans (29%) say COVID-19 made them more worried than ever about having obesity prompting about 28 million people to consider weight-loss methods they hadn’t thought about before the pandemic began, including nearly 6.4 million thought about turning to either weight-loss surgery or taking prescription anti-obesity drugs for the first time, according to a new survey whose findings were published online in the peer-reviewed journal, Surgery for Obesity and Related Diseases (SOARD).
Long-Haul COVID-19 Linked With PTSD, Says Study
Post-acute sequelae SARS-CoV-2 infection (PASC), also known as long-haul COVID-19, is positively associated with posttraumatic stress disorder (PTSD), says new research presented at Physiatry ’23, the Association of Academic Physiatrists (AAP) annual meeting.
COVID-19 is associated with an increased risk to develop gastrointestinal disorders
COVID-19 is associated with an increased risk of developing long-term gastrointestinal disorders, including irritable bowel syndrome.
Trust in cancer information declined among Black Americans during the pandemic
Trust in information given out by the government on cancer fell sharply among the Black population, by almost half, during the COVID-19 pandemic findings of a national US study have shown.
COVID-19 discovery could protect high-risk patients
UVA Health researchers have identified a potential treatment to prevent severe COVID-19 in patients at great risk.
Not getting enough sleep could blunt antibody response to vaccination, leaving you more vulnerable to infection
In reviewing data from previous studies, a team lead by researchers at the University of Chicago and the French National Institute of Health and Medical Research (Inserm) found that individuals who had fewer than six hours of sleep per night in the days surrounding vaccination had a blunted antibody response. That indicates efforts to promote heathy sleep duration ahead of an immunization could be an easy way to improve vaccine effectiveness.
History saved lives in this pandemic. Will society listen next time?
As the pandemic enters its fourth year, the medical historian whose team’s work on the 1918 flu influenced the “flatten the curve” approach in 2020 reflects on what lessons for the future can be drawn by studying recent pandemic history.
On pandemic’s third anniversary, loneliness and isolation are down, but still high, among older adults
After three years of pandemic living, loneliness, isolation and lack of social contact have finally started to decline among older adults, a new poll shows.
The Journal of Medical Internet Research | Chatbot Conversations During COVID-19: Topic Modeling and Sentiment Analysis
This study examined the COVID-19 pandemic–related topics online users discussed with a commercially available chatbot and compared the sentiment expressed by users from five culturally different countries.
Genetic variation that protected against Black Death still helps against respiratory diseases today, but increases autoimmune disease risks
The same genetics that helped some of our ancestors fight the plague is still likely to be at work in our bodies today, potentially providing some of the population with extra protection against respiratory diseases such as COVID-19. However, there is a trade-off, where this same variation is also linked to increased autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease.
COVID-19 infections raise risk of long-term gastrointestinal problems
A new study by researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care system shows that people who have been infected with COVID-19 are at an increased risk of developing a range of gastrointestinal conditions within the first month to a year after illness.
One in Four Parents Misled Others About Their Children Having COVID-19, Survey Finds
More than 25% of parents surveyed report that they were less than truthful about their children’s COVID-19 status or that they didn’t follow the disease’s preventive guidelines during the pandemic for their offspring, according to a nationwide study led in part by University of Utah scientists.
America on the Move: How Urban Travel Has Changed Over a Decade
A new study reveals that although private automobiles continue to be the dominant travel mode in American cities, the share of car trips has slightly and steadily decreased since its peak in 2001. In contrast, the share of transit, non-motorized, and taxicab (including ride-hailing) trips has steadily increased.
Political ideology plays role in how people view boundaries
A new study may reveal part of the reason why conservatives are more likely than liberals to reject some COVID-19 health measures: They see boundaries as restrictions. Liberals were more likely to see some of the measures used in the pandemic – such as social distancing rules and plexiglass separators in restaurants and stores – as providing guidance, rather than restrictions.
More than half of COVID patients suffer long COVID symptoms
Various long-term effects have been found to occur after infection by the novel coronavirus (COVID-19), and the reality of these lingering symptoms remains unknown.
New Study Finds Millions in U.S. Missed Cancer Screening During Second Year of COVID-19 Pandemic
According to a new, nationwide study led by researchers at the American Cancer Society, millions of people in the United States continued to miss critical cancer screening tests during the second year of the COVID-19 pandemic.
Research Team Creates Statistical Model to Predict Covid-19 Resistance
Researchers from Johns Hopkins Medicine and The Johns Hopkins University have created and preliminarily tested what they believe may be one of the first models for predicting who has the highest probability of being resistant to COVID-19 in spite of exposure to SARS-CoV-2, the virus that causes it.
New research reveals possible COVID vaccine blood clot connection
A new Australian study led by SAHMRI and Flinders University has uncovered fundamental differences in how the AstraZeneca and Pfizer COVID-19 vaccines impact the immune system.
Personalized Exercise Program Improves Long COVID Symptoms
A supervised, eight-week exercise program improved symptoms of patients with long COVID better than the current standard self-managed rehabilitation recommendations. The study is published ahead of print in the Journal of Applied Physiology and was chosen as an APSselect article for February.
COVID-19 Vaccination Linked to Fewer Cardiac Events
Analyzing the most extensive datasets in the U.S., researchers from the Icahn School of Medicine at Mount Sinai have revealed that vaccination against COVID-19 is associated with fewer heart attacks, strokes, and other cardiovascular issues among people who were infected with SARS-CoV-2, the virus that causes COVID-19. The research letter, “Impact of Vaccination on Major Adverse Cardiovascular Events in Patients with COVID-19 Infection,” was published in the Journal of the American College of Cardiology on February 20. The research will also be presented on March 5, 2023 in a poster session in New Orleans, LA, at the American College of Cardiology’s 72nd Annual Scientific Session Together With World Heart Federation’s World Congress of Cardiology.
Weaponizing Part of the SARS-CoV-2 Spike Protein Against Itself to Prevent Infection
ROCKVILLE, MD – The virus that causes COVID-19, called SARS-CoV-2, uses its spike protein in order to stick to and infect our cells. The final step for the virus to enter our cells is for part of its spike protein to act like a twist tie, forcing the host cell’s outer membrane to fuse with the virus. Kailu Yang, in the lab of Axel Brunger, colleagues at Stanford University, and collaborators at University of California Berkely, Harvard Medical School, and University of Finland have generated a molecule based on the twisted part of the spike protein (called HR2), which sticks itself onto the virus and prevents the spike protein from twisting.
How COVID-19 Can Impact the Heart
ROCKVILLE, MD – COVID-19 infections can cause potentially life-threatening heart issues. Studies suggest that people with COVID-19 are 55% more likely to suffer a major adverse cardiovascular event, including heart attack, stroke and death, than those without COVID-19. They’re also more likely to have other heart issues, like arrhythmias (abnormal heart rhythms) and myocarditis (inflammation of the heart muscle).
The weight of the COVID-19 pandemic
“A potential pathway between obesity and these stressors could be related to weight bias and stigma; there was extensive media coverage highlighting obesity as a potential risk factor for COVID-19 mortality which may have increased weight stigma,” the researchers wrote. The study examined data from nearly 24,000 participants enrolled in the Canadian Longitudinal Study on Aging (CLSA), who were between the ages of 50 and 96 during the first year of the pandemic. The participants completed the CLSA COVID-19 Questionnaire Study, which collected longitudinal data from April to December 2020. The researchers also used data collected before the pandemic to examine if childhood adversity, such as abuse and neglect, was a factor that modified the relationship between obesity and stress.
Mount Sinai’s Arnhold Institute for Global Health Awarded $8 Million to Expand Global Partnerships in Education and Research
The Arnhold Institute for Global Health at Mount Sinai has received $8 million from the Arnhold Foundation, enabling doctors, researchers, and students to advance its already-strong base of clinical education programs, training, research, and care services to address the world’s leading health issues and improve global health systems.
Chronic Alcohol Use May Increase Risk for SARS-CoV2 Infection, Study Suggests
A newly published animal study found that chronic alcohol consumption may create conditions in the body that can facilitate infection by SARS-CoV2, the virus that causes COVID-19 disease. The study, published in Alcohol: Clinical and Experimental Research, found that chronic alcohol use increased the levels of an enzyme that helps the virus enter the cells and, therefore, may increase the risk for COVID-19.
Employing tradeoffs for more realistic COVID messaging
A Cornell University economist conducted an experiment with nearly 700 people in three countries to gauge the public’s perception of relative risk factors.
Optimal Layout for a Hospital Isolation Room to Contain COVID-19 Includes Ceiling Vent
Researchers recently modeled the transmission of COVID-19 within an isolation room at the Royal Brompton Hospital in London, U.K. Their goal was to explore the optimal room layout to reduce the risk of infection for health care staff. To accomplish this, they used an adaptive mesh finite-element computational fluid dynamics model to simulate 3D spatial distribution of the virus within the room — based on data collected from the room during a COVID-19 patient’s stay. They share their findings and guidance in Physics of Fluids.
Screening teens for vaping history key to diagnosing lung disease during pandemic
The severity of a lung disease associated with e-cigarettes in teens decreased during the COVID-19 pandemic, but hospitalizations from the disease continued to mount, according to a study of more than three dozen patients by UT Southwestern researchers published in Pediatric Pulmonology.
Telemedicine Has Been ‘Hugely Beneficial’ for Health Care, Study Shows
Telemedicine and virtual appointments have become more popular in routine health and wellness since the COVID-19 pandemic began. Cal State Fullerton assistant professor of management David Cho co-authored a study examining the costs and benefits of these services. He notes that the…
Covid-19 in pregnant women can damage the placenta and the fetus
Using prenatal magnetic resonance imaging, a group of MedUni Vienna researchers examined the placentas and foetuses of women who tested positive for SARS-CoV-2 during pregnancy.
QMHC themed issue focuses on diagnosis of COVID-19 in the community
Waltham, MA January 19, 2022: What: Quality Management in Health Care published a themed supplemental issue on the diagnosis of COVID-19 in the community. This issue features several in-depth research articles on an artificial intelligence, web-based decision aid, developed by…
Many older adults declined home medical care for fear of COVID, causing new or worsening conditions
COVID-19 interrupted or delayed medical treatment for many people who chose to put off elective procedures or couldn’t get in to see a specialist.
Vaccination Provides Effective Protection Against Increased Risk of Pregnancy Complications due to COVID-19 Omicron Variant
The global network led by the Oxford Maternal and Perinatal Health Institute (OMPHI) at the University of Oxford has published in the journal Lancet the results of the ‘2022 INTERCOVID Study’ conducted in 41 hospitals across 18 countries, including Ann & Robert H. Lurie Children’s Hospital of Chicago.
UC Irvine, UCLA researchers identify new therapeutic approach to prevent ARDS
A novel peptide designed by University of California, Irvine researchers has been found to suppress the damaging lung inflammation seen in acute respiratory distress syndrome, or ARDS. Their study, which appears in iScience, describes the first specific treatment designed to prevent the deadly disease, which can appear in patients with severe lung injury from infections with bacteria and viruses, like pneumonia, flu, respiratory syncytial virus (RSV) and COVID-19.
Preparing for Coming RSV, Influenza Epidemics
Nonpharmaceutical interventions slowed the spread of COVID-19 and other infectious diseases but now, as NPIs are lifted, countries are seeing a resurgence in several respiratory diseases. In Chaos, scientists, using data from Hong Kong to develop their model, describe a threshold control method that can be used to predict the best time to lift NPIs without overwhelming the hospital systems when these other respiratory diseases inevitably surge back. They found that reintroducing NPI measures when a threshold of 600 severe cases is reached could ensure that the hospital system in Hong Kong is not overwhelmed by severely infected patients.
Surge of SARS-CoV-2 Variants in China and USA Further Emphasizes Need for Surveillance, Preparedness, and International Collaborations
Christian Bréchot, MD, PhD, President of the Global Virus Network (GVN), Associate Vice President for International Partnerships and Innovation at the University of South Florida and Professor of the Division of Infectious Disease, Department of Internal Medicine at USF Health Morsani College of Medicine, the GVN Southeast U.S. Regional Headquarters today issued a statement on the surge of SARS-CoV-2.
Does COVID change the body’s response to other threats? Depends on your sex
The long-term effects of infection on the immune system have long intrigued John Tsang, a Yale immunobiologist. After the body has faced down a pathogen, does the immune system return to the previous baseline? Or does a single infection change it in ways that alter how it will respond not only to a familiar virus but also to the next new viral or bacterial threat it faces?