CHOP Researchers Find COVID-19 Vaccination Leads to Higher Antibody Levels than Natural Infection in Both Pregnant People and their Babies

Pregnant people who received one of the mRNA COVID-19 vaccines had 10-fold higher antibody concentrations than those who were naturally infected with SARS-CoV-2, a finding that was also observed in their babies, according to a new study by researchers at Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania. The study, published today in JAMA Network Open, also found that vaccine timing played an important role in maximizing the transfer of antibodies, with antibodies detected as early as 15 days after the first vaccine dose and increasing for several weeks after.

CHOP Study Finds Neighborhood Poverty and Crowding Associated with Higher Rates of COVID-19 in Pregnancy

Neighborhood characteristics, including poverty and crowding within homes, were associated with higher rates of SARS-CoV-2 in pregnancy during the prevaccination era of the pandemic, according to a new study led by researchers at Children’s Hospital of Philadelphia (CHOP). The findings, which were published today in the journal Obstetrics and Gynecology, may partially explain the high rates of COVID-19, the disease caused by SARS-CoV-2, among Black and Hispanic patients.

Is it Safe to Get COVID-19 Vaccine while Pregnant?

Justin Brandt, an assistant professor in the Division of Maternal Fetal Medicine at Rutgers Robert Wood Johnson Medical School and director of quality and safety for the department of OB/GYN, talks about the information provided by the Centers for Disease Control and Prevention and what pregnant women should consider when deciding whether to get the COVID-19 vaccine.