The Future of Medicine Rises in University City: University of Pennsylvania Opens New Multi-Disciplinary Research Labs in One uCity Square

Wexford Science & Technology, LLC and the University of Pennsylvania today announced that the University has signed a lease for new laboratory space that will usher in a wave of novel vaccine, therapeutics and engineered diagnostics research to West Philadelphia.

Clinical Labs’ Quick Response to COVID-19 Helped Reduce Hospitalizations and Save Lives

A new survey from the Association for Diagnostics & Laboratory Medicine (formerly AACC) found that clinical labs’ robust, rapid response to the COVID-19 pandemic helped to contain the virus and save lives. However, the challenges labs faced with insufficient supplies and staffing shortages have only intensified since 2020. The percentage of laboratory professionals reporting staffing issues rose steadily from 35.4% in May 2020 to 87.5% in January 2022—raising questions about whether labs would have the necessary resources to respond to a similar public health emergency today.

Dr. Carol Nwelue discusses how to keep your kids healthy when going back to school.

Carol Nwelue, MD, at Baylor Scott & White Health, answers common patient questions and reacts to the latest medical research. How can parents keep their kids healthy this back-to-school season? (SOT@ 0:14, TRT 0:34) Why do sicknesses spread easily when…

Rather than providing protection, an Omicron infection may leave patients more susceptible to future COVID infections, researchers find after studying seniors in care

Researchers at McMaster University have found that rather than conferring immunity against future infections, infection during the first Omicron wave of COVID left the seniors they studied much more vulnerable to reinfection during the second Omicron wave.

Long-Term Study Reaffirms Benefits of Covid-19 Vaccination for Organ Transplant Recipients

A two-year study found that spikes of post-vaccination SARS-CoV-2 viral infections (commonly known as COVID-19 breakthrough cases) remain common, yet hospitalization rates have dramatically dropped following the first wave of the virus’ omicron subvariant.

Dr. Marc Elieson discusses concerns about COVID-19 and kids going back to school

Marc Elieson, MD, at Baylor Scott & White Health, answers common patient questions and reacts to the latest medical research. The CDC says COVID cases will continue to increase this summer and when school resumes this fall. What is behind…

International Study Shows that Taste, Independent of Smell, Can Also be Significantly Diminished in Patients with COVID-19

Smell loss became the cardinal symptom of COVID-19 early in the pandemic and has ignited research on how smell and taste function. An international study led by the Global Consortium for Chemosensory Research (GCCR) and the Monell Chemical Senses Center has untied taste from smell in people with COVID-19, demonstrating in a large and diverse group of more than 10,000 people that taste, independent of smell, is also greatly impacted by COVID.

More Than 2 Million Additional Americans Faced Food Insufficiency Following Drawdown of Pandemic-Related SNAP Benefits, Penn Medicine Study Finds

The recent discontinuation of pandemic-related food assistance benefits, known as the Supplemental Food Assistance Program (SNAP) Emergency Allotments, led to a substantial increase in food insufficiency in the United States, according to a new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania.

Study Reveals Patients Hospitalized with COVID-19 Faced Nearly Twice the Rates of Death After Discharge As Patients with Flu

Researchers demonstrate that among individuals who were admitted to the hospital with COVID-19 and were discharged alive, the risk of post-discharge death was nearly twice that observed in those who were discharged alive from an influenza-related hospital admission.

Early-Stage Cancer Diagnoses Decreased Sharply in the U.S. During First Year of COVID-19 Pandemic; Underserved Greatly Affected

A new study from researchers at the American Cancer Society found monthly adult cancer diagnoses decreased by half in April 2020 during the COVID-19 pandemic in the United States. The largest decrease was for stage I cancers, resulting in a higher proportion of late-stage diagnoses.

ACP Says the U.S. Needs Immediate Action to Prepare for Future Pandemics

The United States has significant gaps in its pandemic and public health emergency response system leaving it unprepared for future emergencies, says the American College of Physicians (ACP) in a new policy paper. In the paper, ACP makes recommendations about what needs to be done to ensure the U.S. is in a strong position to mitigate the consequences of future pandemics. The paper is published in Annals of Internal Medicine.

Promising Results of Next-Generation Intranasal COVID-19 Booster Vaccine: Implications for Infection Prevention and Transmission

The Icahn School of Medicine at Mount Sinai in New York, NY is pleased to announce that CastleVax, Inc. has completed enrollment and a preliminary analysis of a phase 1 trial of its licensed Newcastle disease virus (NDV)-based COVID-19 booster vaccine.

Gene Mutation May Explain Why Some Don’t Get Sick from COVID-19

People who contract COVID-19 but never develop symptoms – the so-called super dodgers – may have a genetic ace up their sleeve. They’re more than twice as likely as those who become symptomatic to carry a specific gene variation that helps them obliterate the virus, according to a new study led by UC San Francisco researchers. 

Early COVID-19 pandemic not associated with significant physician turnover

An analysis of Medicare billing has found that physician turnover rates between 2010 and 2020 had both periods of increase and stability, with annual turnover rising from 5.3% to 7.6% (43%), between 2010 and 2018. However, early data covering the first three quarters of 2020 did not show that the early COVID-19 pandemic caused significant physician turnover. The analysis is published in Annals of Internal Medicine.

Air monitor can detect COVID-19 virus variants in about 5 minutes

Now that the emergency phase of the COVID-19 pandemic has ended, scientists are looking at ways to surveil indoor environments in real time for viruses. By combining recent advances in aerosol sampling technology and an ultrasensitive biosensing technique, researchers at Washington University in St. Louis have created a real-time monitor that can detect any of the SARS-CoV-2 virus variants in a room in about 5 minutes.

ASA and APSF Release Updated Recommendations for Elective Surgery After COVID-19 Infection

Driven by recent studies, the evolving nature of the disease and the widespread vaccination of Americans against COVID-19, the American Society of Anesthesiologists (ASA) and Anesthesia Patient Safety Foundation (APSF) today released a joint statement providing updated recommendations for the timing of elective surgeries and anesthesia for patients after a COVID-19 infection.

Pandemic Alcohol Use Linked to Nervous System Disruption in Pregnant and Postpartum Women, Hinting at Novel Clinical Biomarker and Intervention Potential

Increased alcohol use among pregnant and postpartum women during the COVID-19 pandemic was associated with autonomic nervous system dysregulation, known to negatively affect resilience to change and further exacerbate the risk of stress-related mental health disorders and substance use, a new study suggests. The findings, although preliminary, underline the potential for a new clinical biomarker and novel personalized mobile health apps in facilitating treatment interventions. Previous research linked the pandemic to increased stress levels and drinking, including in pregnant and postpartum women. Alcohol use, and stress-related conditions such as depression and anxiety, are associated with dysregulation in the feedback loop between the body and the brain. This process involves the peripheral autonomic nervous system, which regulates the heartbeat. Healthy, resilient people tend to have higher heart rate variability than people with stress and substance use disorders. Heart rate variab

Why Do Some Long Covid Patients Continue to Have Difficulty Exercising?

In a study published in the Journal of Infectious Diseases, a team of researchers from UC San Francisco found that lower than expected exercise capacity was common among people with Long COVID and chronotropic incompetence (inadequate heart rate increase during exercise) was the most common reason. They also found reduced exercise capacity to be correlated with early post-Covid elevations of inflammatory biomarkers. In addition, they found that reactivation of Epstein-Barr virus (EBV) may be related to reduced heart rate while exercising.

USU Study finds National Guard members remained psychologically resilient during pandemic response

The National Guard (NG) played a crucial role in the nation’s response to the COVID-19 pandemic, assisting communities nationwide with emergency outreach, setting up care facilities, working at testing sites, and distributing supplies, among many other demands. Simultaneously, these service members faced their own personal and family responses to the crisis. Still, they remained psychologically resilient, according to a new study led by the Uniformed Services University’s (USU) Center for the Study of Traumatic Stress (CSTS).

AACN Practice Alert Offers Guidance on Manual Prone Positioning for Patients With ARDS

A newly released practice alert from the American Association of Critical-Care Nurses aims to standardize how nurses care for patients undergoing prone positioning therapy for extended periods of time. It summarizes expected nursing practice to reduce the risk of complications related to manual prone positioning.

Experts say it’s not yet time to take off masks in the health care setting

A new commentary from infectious disease experts at George Washington University School of Medicine and the National Institutes of Health (NIH) says for patient safety, masking should continue in health care settings. This message conflicts with a recent commentary from authors from 8 U.S. institutions suggesting that the time for universal masking is over. The commentary is published in Annals of Internal Medicine.

Adding a single data point to COVID-19 reporting may more accurately convey the real-time burden of infection in health care settings

In a new ‘Medicine and Public Issues,’ authors from Tufts Medical Center, Veterans Affairs Boston Healthcare System, Harvard Medical School and the Massachusetts Department of Public Health advocate for the inclusion of both the total number of COVID-19 hospitalizations daily and the number of inpatients who received dexamethasone at any point during their hospital stay. The authors emphasize that the addition of this data element is an easy and much-needed update to COVID-19 surveillance efforts that may help to more accurately convey the real-time burden of a rapidly changing infection in health care settings. The article is published in Annals of Internal Medicine.

Updated evidence suggests masks may reduce risk for SARS-CoV-2 infection in community and health care settings

The final and major update to a rapid, living review of published evidence suggests that masks may be associated with a small reduction in risk for COVID-19 infection in community settings versus no mask use and both surgical masks and N95 respirators may be associated with similar infection risk in routine patient care settings. However, a beneficial effect of N95 respirators could not be ruled out in the health care setting. The review is published in Annals of Internal Medicine.

SARS-CoV-2 seasonal behavior traced back to genetics and global change

As the northern hemisphere heads into summer, we may be in for a COVID-19 reprieve. Not because the pandemic is over; the Omicron subvariant ‘Arcturus’ is still creeping upward and causing new symptoms. But two new studies from the University of Illinois add evidence supporting a seasonal pattern in the behavior of the SARS-CoV-2 virus.