Multiple sclerosis drug works in a surprising way

Drugs called interferon betas are common treatments for multiple sclerosis. Interferon beta, a protein known to contain a zinc-binding pocket, is thought to reduce proinflammatory molecules in MS patients. But researchers now report in ACS Chemical Neuroscience that the molecule reduces the binding of three components — zinc, C-peptide and albumin — to red blood cells.

New drug candidate fights off more than 300 drug-resistant bacteria

Urinary tract infections are common, yet can be tough to treat as the bacteria that cause them become resistant to many antibiotics. In ACS Central Science, researchers report a new molecule that inhibits drug-resistant bacteria in lab experiments, as well as in mice with pneumonia and UTIs.

People respond differently to psychedelic drugs — genetics could be the reason

Psychedelic drugs have shown benefits as treatments for cluster headaches, anxiety and depression in clinical studies, but not for everyone. Now, in ACS Chemical Neuroscience, researchers report that one reason could be common genetic variations in one serotonin receptor.

Crop Protection: Biohacking against Fungal Attacks

Harmful fungi cause enormous agricultural losses. Conventional techniques for combating them involve the use of poisonous fungicides. Researchers at Karlsruhe Institute of Technology (KIT), working with partners from Germany, France, and Switzerland on the DialogProTec project, have developed environmentally safe alternatives that trick the pathogens’ chemical communication with plants. Now that the research has been completed, the new technology is ready for use.

Turning white blood cells into medicinal microrobots with light

Researchers reporting in ACS Central Science have used lasers to precisely control neutrophils — a type of white blood cell — as a natural, biocompatible microrobot in living fish. The “neutrobots” performed multiple tasks, showing they could someday deliver drugs to precise locations in the body.

Tabletop Magnetic Resonance Units to Revolutionize Diagnostics and Materials Analysis

In the HyPERiON CRC coordinated by the Karlsruhe Institute of Technology (KIT), researchers from KIT and the universities of Kaiserslautern, Konstanz and Stuttgart are jointly developing technology for compact high-performance magnetic resonance units. In the future, the devices could be used in the chemical and pharmaceutical industries, in medical practices or at border checkpoints. The German Research Foundation is funding the interdisciplinary group with more than 10.6 million euros for four years starting on July 1, 2022.

These energy-packed batteries work well in extreme cold and heat

Researchers developed lithium-ion batteries that perform well at freezing cold and scorching hot temperatures, while packing a lot of energy. This could help electric cars travel farther on a single charge in the cold and reduce the need for cooling systems for the cars’ batteries in hot climates.

Thin-film Photovoltaic Technology Combines Efficiency and Versatility

Stacking solar cells increases their efficiency. Working with partners in the EU-funded PERCISTAND project, researchers at the Karlsruhe Institute of Technology (KIT) have produced perovskite/CIS tandem solar cells with an efficiency of nearly 25 percent – the highest value achieved thus far with this technology. Moreover, this combination of materials is light and versatile, making it possible to envision the use of these tandem solar cells in vehicles, portable equipment, and devices that can be folded or rolled up. The researchers present their results in the journal ACS Energy Letters (DOI: 10.1021/acsenergylett.2c00707)

Press registration opens for the hybrid ACS Fall 2022 meeting

The American Chemical Society’s ACS Fall 2022 will be held virtually and in Chicago Aug. 21–25 with the theme “Sustainability in a Changing World.” ACS considers requests for press credentials and complimentary meeting registration from reporters and public information officers at selected institutions.

Closed-loop additive manufacturing fueled by upcycled plastic

Researchers at the Department of Energy’s Oak Ridge National Laboratory have developed an upcycling approach that adds value to discarded plastics for reuse in additive manufacturing, or 3D printing. The readily adoptable, scalable method introduces a closed-loop strategy that could globally reduce plastic waste and cut carbon emissions tied to plastic production.

Electrolyte Additive Offers Lithium Battery Performance Breakthrough

UPTON, NY—A team of researchers led by chemists at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory has learned that an electrolyte additive allows stable high-voltage cycling of nickel-rich layered cathodes. Their work could lead to improvements in the energy density of lithium batteries that power electric vehicles.

CityU co-hosts online science and tech conference with Nature journals; pre launch for CityU’s HK Tech Forum

Leading scientists exchanged innovative views on contemporary trends in the chemistry of 2D materials at a three-day online conference co-organised by City University of Hong Kong (CityU) and Nature Conferences, the preeminent series curated by the highly prestigious science journal Nature and Nature journals.

Machine Learning Framework IDs Targets for Improving Catalysts

Chemists at the U.S. Department of Energy’s Brookhaven National Laboratory have developed a new machine-learning (ML) framework that can zero in on which steps of a multistep chemical conversion should be tweaked to improve productivity. The approach could help guide the design of catalysts — chemical “dealmakers” that speed up reactions.

Brookhaven Chemist Minfang Yeh Wins 2021 DPF Instrumentation Award

UPTON, NY—Minfang Yeh, a senior scientist at the U.S. Department of Energy’s Brookhaven National Laboratory, has won the American Physical Society’s 2021 Division of Particles and Fields (DPF) Instrumentation Award. The award honors Yeh’s pioneering work in the development and production of high-performance water-based liquid scintillators for particle physics experiments, including metal loaded scintillators for rare process experiments.

A midge fly can be a source of currently used pesticides for birds, bats

Researchers reporting in ACS’ Environmental Science & Technology have observed that non-biting midge larvae accumulate contemporary pesticides from polluted water and retain the substances into adulthood. As a result, animals that eat the adult flies could consume small amounts of pesticides daily.

Not so Basic: Advances in pH and Phosphate Monitoring Enhance Safety in Nuclear Fuel Recycling

Two PNNL interns are behind recent innovation in real-time testing and continuous monitoring for pH and the concentration of chemicals of interest in chemical solutions; outcomes have applicability not only to nuclear, but to industries.