MEDIA ADVISORY: Cedars-Sinai Physicians, Scientists Featured at Otolaryngology-Head and Neck Surgery Conference

Physicians and scientists from Cedars-Sinai will be attending and sharing research and clinical breakthroughs at the American Rhinologic Society Annual Meeting (ARS) taking place Sept. 9-10, the American Neurotology Society (ANS) “Super Saturday” Meeting Sept. 10, and the American Academy of Otolaryngology-Head and Neck Surgery Annual Meeting (AAO-HNSF22) taking place Sept. 10-14, in Philadelphia.

August Research Highlights

A Roundup of the Latest Medical Discoveries and Faculty News at Cedars-Sinai

Cedars-Sinai Team Pioneers Liver Cancer Blood Test

Cedars-Sinai Cancer investigators have created a blood test that uses a technology made commonly available during the COVID-19 pandemic to detect the most common form of liver cancer—at an early enough stage that cure is possible. Their work was published online in the peer-reviewed journal Hepatology.

Late-Breaking Heart Research: AI More Accurate Than Technicians

In a first-of-its-kind randomized clinical trial led by researchers at the Smidt Heart Institute and the Division of Artificial Intelligence in Medicine at Cedars-Sinai, artificial intelligence (AI) proved more successful in assessing and diagnosing cardiac function when compared to echocardiogram assessments made by sonographers.

How Tumors Make Immune Cells ‘Go Bad’

Investigators from Cedars-Sinai Cancer have discovered that cancerous tumors called soft-tissue sarcomas produce a protein that switches immune cells from tumor-attacking to tumor-promoting. The study, published today in the peer-reviewed journal Cell Reports, could lead to improved treatments for soft-tissue sarcomas.

Genetic Score Detects Those at Risk for Sudden Cardiac Death

Researchers in the Smidt Heart Institute at Cedars-Sinai are one step closer to identifying patients at highest risk for developing sudden cardiac death—an electrical malfunction in the heart that causes it to stop beating.

Smidt Heart Institute Experts to Present Innovative Research Findings at European Society of Cardiology Congress 2022

Experts from the Smidt Heart Institute at Cedars-Sinai, home to California’s top-ranked cardiology and heart surgery programs, will present an array of innovative research—including late-breaking science—during the European Society of Cardiology Congress 2022, taking place in person and virtually Aug. 26-29.

Hyperactivation of the Immune System May Cause Post-COVID Syndromes

Investigators at Cedars-Sinai have proposed a theory for how SARS-CoV-2, the virus that causes COVID-19, infects the body. Their hypothesis, published in Frontiers in Immunology, could explain why some people still have symptoms long after the initial infection.

Q&A: Advice for a Healthy, Stress-Free Return to School

For the past two-plus years, the COVID-19 pandemic has disrupted children’s education and frustrated parents. Today, with the back-to-school season in full swing, Suzanne Silverstein, MA, ART, founding director of Cedars-Sinai Share & Care, and Rose Bisellach, RN, nurse manager in the Providence Cedars-Sinai Tarzana Medical Center Emergency Room, give their best advice for starting a successful school year.

Radiation Oncology Expert Joins Cedars-Sinai Cancer

Marc Botnick, MD, a board-certified radiation oncologist with more than 20 years of experience managing all cancer types, has been named regional medical director for Radiation Oncology at Cedars-Sinai Cancer. His primary clinical practice site will be at Cedars-Sinai Tarzana Radiation Oncology, but he will work closely with physicians throughout the enterprise.

Cedars-Sinai Lung Transplant Outcomes Rated Outstanding

A new report on lung transplantation success rates confirms that Cedars-Sinai patients experienced one-year survival outcomes of 91.49%, an achievement above the national average of 89.46%.

Stroke Biomarker, Health Equity Expert Joins Cedars-Sinai

Alexis Simpkins, MD, PhD, a stroke expert whose research focuses on acute stroke treatment and prevention, advanced brain imaging, and improving health equity in patient care and diversity among trainees in stroke, has joined the faculty in the Department of Neurology at Cedars-Sinai as director of Vascular Neurology Research and the Stroke RNA, Imaging, and Protein Predictors for Patient Tailored Treatments (SkRIPT) Program.

Standing Up to Stage 4 Breast Cancer

Holly Hammond faced one of the toughest-imaginable breast cancer scenarios. Her cancer was already advanced and had spread to her liver and lymph nodes when she discovered a tumor on her right breast. The tumor was negative for all of the markers that respond to targeted therapies for cancer treatment. She was also positive for the genes that mark her as especially prone to breast cancer.

Genetics May Predict Bladder Cancer Immunotherapy Response

Investigators from Cedars-Sinai Cancer have identified genetic signatures that could predict whether tumors in patients with bladder and other cancers will respond to immunotherapy. Their results, published today in the peer-reviewed Journal of the National Cancer Institute, could one day help guide clinicians to the most effective treatments for cancer patients.

New National Guidelines Aim to Prevent Obesity in Midlife Women

Women between 40 and 60 years old are the focus of new national guidelines aimed at preventing unhealthy weight gain that can lead to serious illness. The study review paper and clinical guidelines are published in the Annals of Internal Medicine.

Cedars-Sinai’s Howard Sandler, MD, Elected President of ASTRO

Howard Sandler, MD, chair of the Department of Radiation Oncology at Cedars-Sinai Cancer, has been named president-elect of the American Society for Radiation Oncology (ASTRO). Sandler will begin his term as president-elect in October, followed by single-year terms as president, chair and then immediate past chair of the ASTRO Board.

Preclinical Study: Antibiotics Affect Male and Female Gut Microbiomes Differently

In a new study, researchers at Cedars-Sinai found that antibiotics have sex-specific effects on the gut microbiome makeup of male and female laboratory rats. The findings, published in the journal Frontiers in Microbiology, could have implications for using the drugs in humans to treat or prevent bacterial infection.

Hypertension Elevates Risk for More Severe COVID-19 Illness

Hypertension more than doubles the risk of hospitalization related to Omicron infection, even in people who are fully vaccinated and boosted, according to a new study led by investigators in the Smidt Heart Institute at Cedars-Sinai. The findings are published in the journal Hypertension.

Cedars-Sinai Ranked #2 Hospital in Nation by U.S. News & World Report

Cedars-Sinai has been named the #2 hospital in the nation and #1 in California in U.S. News & World Report’s “Best Hospitals 2022-23” rankings.

A First Look at Cedars-Sinai Guerin Children’s

Inside the new, 23,000-square-foot Guerin Children’s, walls are painted in cheerful yellows, greens and blues. Artificial skylights are timed to brighten and darken as the sun rises and sets. Interactive-art installations feature whimsical characters, and a playroom and family lounge area contribute to the playful energy of the space.

A Lifetime of Heart Care Leads to Transplant

While many 21-year-olds celebrate their coming of age in bars and nightclubs, Andrew Solis is celebrating freedom by finally going home—equipped with a new heart and liver—after nearly eight months at Cedars-Sinai.

Hormones Contribute to Sex Disparities in Bladder Cancer, Study Shows

Male sex hormones interfere with the body’s ability to fight bladder cancer, likely explaining why males experience higher cancer rates and more deadly disease, according to a new study co-led by a Cedars-Sinai Cancer investigator.

First-of-its-Kind Stem Cell and Gene Therapy Highlighted at Annual Stem Cell Meeting

Investigators from Cedars-Sinai will present the latest novel stem cell and regenerative medicine research at the International Society for Stem Cell Research (ISSCR) Annual Meeting, which is being held in person and virtually June 15-19 in San Francisco.

Path to Remission for a Brain Cancer That Is Usually Fatal

Recently, Michael Wulfe, who is 61 and lives in West Hollywood, was on the phone with his sister, Stephanie Wulfe, in Dallas. They talk at least once a day, but that day, something wasn’t right. “I was talking, and then I didn’t have the words,” Wulfe said. “My sister immediately said, ‘Call Cedars-Sinai!’”

National Leader in Cardiac Surgery Quality and Research Joins Cedars-Sinai

Michael Bowdish, MD, MS, a national leader in cardiac surgery and among a handful of cardiac surgeons continuously funded by the National Institutes of Health for a decade, has been appointed vice chair of the Department of Cardiac Surgery in the Smidt Heart Institute.

ASCO22: Lung Cancer Therapy Could Help Patients Live Longer

Results of a Phase II clinical trial led by Cedars-Sinai Cancer investigators indicate that an immunotherapy drug combination could extend the lives of those diagnosed with advanced non-small cell lung cancer, one of the most common forms of lung cancer. The research was presented today during the American Society of Clinical Oncology (ASCO) annual meeting in Chicago, with simultaneous publication in the peer-reviewed Journal of Clinical Oncology.

ENDO 2022 to Feature Cedars-Sinai Physicians and Scientists

Physicians and scientists from Cedars-Sinai will discuss the latest advances in treatment, care and research at the Endocrine Society’s annual meeting (ENDO 2022) in Atlanta, June 11-14.

Brain Cell Activity Plays Critical Role in CNS Disorder Outcomes

Investigators at Cedars-Sinai have comprehensively mapped molecular activity in the brain and spinal cord that is responsible for regulating the body’s response to central nervous system (CNS) disorders such as Alzheimer’s, Huntington’s disease and spinal cord injuries.

SpaceX CRS-25 to Launch Stem Cells to Space on June 9

Cedars-Sinai and Space Tango are launching pilot-scale systems for the in-space production of stem cells to see if they can elevate the next generation of stem cell and gene therapies by harnessing the near-zero gravity conditions of spaceflight.