Tag: Castleman Disease

Cleveland Clinic Researchers Uncover How Virus Causes Cancer, Point to Potential Treatment

sarah JonasResearch Results

Cleveland Clinic researchers have discovered a key mechanism used by Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), to induce cancer. The research points to effective new treatment options for KSHV-associated cancers, including Kaposi’s sarcoma, primary effusion lymphoma, and HHV8-associated multicentric Castleman disease.

Researchers Discover Test to Predict Which Patients with Rare Blood Disease Will Respond to Only FDA-Approved Treatment, and Identify Alternative Therapy

sarah JonasResearch Results

New research has uncovered a precision medicine test using blood proteins to identify a novel patient subgroup of idiopathic multicentric Castleman disease (iMCD), a rare blood disorder, who are more likely to respond to siltuximab, the only FDA approved treatment for the disease.