QUT researchers have used nationwide cancer mapping statistics to develop a new mathematical model so health professionals can further question patterns relating to the disease. Epidemiologists use disease atlases to identify disease prevalence and mortality rates and QUT researchers say…
Tag: CARCINOGENS
Culling cancer before it stems: A novel, rapid carcinogen detection method
Scientists develop a simple and quick method involving stem cells to test chemicals for their carcinogenicity, which gives results in just seven days
Dozens of pesticides linked with mammary gland tumors in animal studies
Findings have implications for how federal agencies assess pesticides for breast cancer risk
Night-time exposure to blue light associated with increased risk of colorectal cancer
Blue light has become an increasingly common component of urban outdoor lighting. But how does it impact our health? A team led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by the “la Caixa” Foundation, has conducted the…
Oncotarget: Therapeutic efficacy of liposomal Grb2 antisense oligodeoxynucleotide (L-Grb2)
The cover for issue 29 of Oncotarget features Figure 5, “In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model,” by Lara, et al. which reported that adaptor proteins such as growth factor receptor-b
New partnership set to examine how algae could be key to safer sunscreens
A Swansea University project exploring how to use algae to create the next generation of sunscreens has now teamed up with an award-winning skincare firm to help develop the idea
Cancer researcher named UC Riverside medical school’s newest endowed chair
Adam Godzik has been named the Bruce D. and Nancy B. Varner Presidential Endowed Chair in Cancer Research
Cancer researcher named UC Riverside medical school’s newest endowed chair
Adam Godzik has been named the Bruce D. and Nancy B. Varner Presidential Endowed Chair in Cancer Research
What silicone wristbands say about chemical exposure in Uruguayan children
A study examines chemical exposure in a small group of 6- to 8-year-olds in Montevideo, Uruguay
Oncotarget: Mutation profile of primary subungual melanomas in Caucasians
Volume 11 Issue 25 of Oncotarget reported that this study aimed to define the mutation profile of SUM in Caucasians
Oncotarget: RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation
The cover for issue 25 of Oncotarget features Figure 8, ‘BI-D1870 in combination with vincristine increase metaphase arrest and apoptosis synergistically,’ by Chae, et al.
Oncotarget: Tumor suppressor p53 regulates insulin receptor gene expression
Volume 11, Issue 25 of Oncotarget reported that the present study was aimed at evaluating the hypothesis that p53 governs the expression and activation of the INSR gene in breast cancer cells
Postoperative atrial fibrillation does not impact on overall survival after esophagectomy
Volume 11, Issue 25 of Oncotarget reported that Administration of landiolol hydrochloride was found to be associated with reduced incidence of atrial fibrillation after esophagectomy for esophageal cancer in our previous randomized controlled trial
Oncotarget: Bacteriome and mycobiome and bacteriome-mycobiome interactions
Volume 11 Issue 25 of Oncotarget reported that the authors aimed to characterize the bacteriome, mycobiome, and mycobiome-bacteriome interactions of oral wash in Head and neck squamous cell carcinoma, or HNSCC
Oncotarget: Indoximod opposes the immunosuppressive effects mediated by IDO and TDO
Volume 11 Issue 25 of Oncotarget reported that Indoximod has shaped the understanding of the biology of IDO1 in the control of immune responses, though its mechanism of action has been poorly understood
Oncotarget: Mutation profile of primary subungual melanomas in Caucasians
Volume 11 Issue 25 of Oncotarget reported that this study aimed to define the mutation profile of SUM in Caucasians
Oncotarget: RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation
The cover for issue 25 of Oncotarget features Figure 8, ‘BI-D1870 in combination with vincristine increase metaphase arrest and apoptosis synergistically,’ by Chae, et al.
Oncotarget: Tumor suppressor p53 regulates insulin receptor gene expression
Volume 11, Issue 25 of Oncotarget reported that the present study was aimed at evaluating the hypothesis that p53 governs the expression and activation of the INSR gene in breast cancer cells
Postoperative atrial fibrillation does not impact on overall survival after esophagectomy
Volume 11, Issue 25 of Oncotarget reported that Administration of landiolol hydrochloride was found to be associated with reduced incidence of atrial fibrillation after esophagectomy for esophageal cancer in our previous randomized controlled trial
Oncotarget: Bacteriome and mycobiome and bacteriome-mycobiome interactions
Volume 11 Issue 25 of Oncotarget reported that the authors aimed to characterize the bacteriome, mycobiome, and mycobiome-bacteriome interactions of oral wash in Head and neck squamous cell carcinoma, or HNSCC
Oncotarget: Indoximod opposes the immunosuppressive effects mediated by IDO and TDO
Volume 11 Issue 25 of Oncotarget reported that Indoximod has shaped the understanding of the biology of IDO1 in the control of immune responses, though its mechanism of action has been poorly understood
A novel radioisotope therapy for children with neuroblastoma
Researchers from Kanazawa University discover that high-dose 131I-metaiodobenzylguanidine treatment could provide a favorable prognosis in children with neuroblastoma
Oncotarget: Preoperative geriatric nutritional risk index is a useful prognostic indicator
The cover for issue 24 of Oncotarget features Figure 4, ‘Cancer-specific survival curves based on GNRI according to pTNM stage,’ by Hirahara, et al.
Oncotarget: Preoperative geriatric nutritional risk index is a useful prognostic indicator
The cover for issue 24 of Oncotarget features Figure 4, ‘Cancer-specific survival curves based on GNRI according to pTNM stage,’ by Hirahara, et al.
5 Pew-Stewart scholars selected to spearhead innovative cancer research
PHILADELPHIA–The Pew Charitable Trusts and the Alexander and Margaret Stewart Trust announced today the 2020 class of the Pew-Stewart Scholars Program for Cancer Research. The five early-career scholars who make up the 2020 class will each receive a four-year grant…
5 Pew-Stewart scholars selected to spearhead innovative cancer research
PHILADELPHIA–The Pew Charitable Trusts and the Alexander and Margaret Stewart Trust announced today the 2020 class of the Pew-Stewart Scholars Program for Cancer Research. The five early-career scholars who make up the 2020 class will each receive a four-year grant…
Oncotarget: Hyperprogression to immune blockade followed by a response with cabozantinib
Volume 11, Issue 22 of @Oncotarget reported that more and more patients receive first-line treatment with immunotherapy combinations and not all patients respond in metastatic renal cell carcinoma.
Oncotarget: miR-151a enhances Slug dependent angiogenesis
Volume 11, Issue 23 of @Oncotarget reported that the authors have previously established that mi R-151a functions as an onco-mi R in non-small cell lung cancer cells by inducing partial EMT and enhancing tumor growth.
Oncotarget: The role of EGFR mutations in predicting recurrence in lung adenocarcinoma
Volume 11, Issue 22 of @Oncotarget reported that while lobectomy can improve mortality in this group, about 30 55% of patients will experience disease recurrence.
Oncotarget: Adoptive cell therapy in combination with checkpoint inhibitors
Volume 11, Issue 22 of @Oncotarget reported that there are rationale and evidence supporting immune therapy in Ovarian Cancers. The authors investigated the potential for adoptive cell therapy from in vitro expanded tumor-infiltrating lymphocytes in combi
Oncotarget: Exploring the role of survivin in neuroendocrine neoplasms
Volume 11, Issue 23 of @Oncotarget reported that tissue microarrays of 132 patients were stained for survivin using immunohistochemistry and correlated with outcomes
Oncotarget: Hyperprogression to immune blockade followed by a response with cabozantinib
Volume 11, Issue 22 of @Oncotarget reported that more and more patients receive first-line treatment with immunotherapy combinations and not all patients respond in metastatic renal cell carcinoma.
Oncotarget: miR-151a enhances Slug dependent angiogenesis
Volume 11, Issue 23 of @Oncotarget reported that the authors have previously established that mi R-151a functions as an onco-mi R in non-small cell lung cancer cells by inducing partial EMT and enhancing tumor growth.
Oncotarget: The role of EGFR mutations in predicting recurrence in lung adenocarcinoma
Volume 11, Issue 22 of @Oncotarget reported that while lobectomy can improve mortality in this group, about 30 55% of patients will experience disease recurrence.
Oncotarget: Adoptive cell therapy in combination with checkpoint inhibitors
Volume 11, Issue 22 of @Oncotarget reported that there are rationale and evidence supporting immune therapy in Ovarian Cancers. The authors investigated the potential for adoptive cell therapy from in vitro expanded tumor-infiltrating lymphocytes in combi
Oncotarget: Exploring the role of survivin in neuroendocrine neoplasms
Volume 11, Issue 23 of @Oncotarget reported that tissue microarrays of 132 patients were stained for survivin using immunohistochemistry and correlated with outcomes
Continued nicotine use promotes brain tumors in lung cancer patients, study suggests
Wake Forest researchers suggest nicotine replacement therapies may not be suitable smoking cessation strategies for this population
Continued nicotine use promotes brain tumors in lung cancer patients, study suggests
Wake Forest researchers suggest nicotine replacement therapies may not be suitable smoking cessation strategies for this population
Oncotarget: Anticancer effect of physical activity is mediated
Volume 11, Issue 22 of Oncotarget reported that the goal of this study was to explore the involvement of mi RNAs in beneficial effects exerted by physical activity in breast cancer prevention
Oncotarget: Second line trastuzumab emtansine following horizontal dual blockade
Volume 11, Issue 22 of Oncotarget reported that despite relevant medical advancements, metastatic breast cancer remains an incurable disease
Oncotarget: Anticancer effect of physical activity is mediated
Volume 11, Issue 22 of Oncotarget reported that the goal of this study was to explore the involvement of mi RNAs in beneficial effects exerted by physical activity in breast cancer prevention
Oncotarget: Second line trastuzumab emtansine following horizontal dual blockade
Volume 11, Issue 22 of Oncotarget reported that despite relevant medical advancements, metastatic breast cancer remains an incurable disease
Aluminum oxide crystal tested as a UV radiation sensor
Doped with carbon and magnesium, the material becomes thermoluminescent in response to UV radiation
Mapping immune cells in brain tumors
The removal of a malignant brain tumor is something of a balancing act between removing as much tumor tissue as possible at the same time as protecting the healthy tissue. Since cancer cells infiltrate healthy brain tissue, it is often…
Mapping immune cells in brain tumors
The removal of a malignant brain tumor is something of a balancing act between removing as much tumor tissue as possible at the same time as protecting the healthy tissue. Since cancer cells infiltrate healthy brain tissue, it is often…
An exploratory study of metformin and rapamycin as maintenance therapy
Volume 11, Number 21 of Oncotarget reported that eligible patients with stable or responding mPDA after 6 months on chemotherapy were randomized 1:1 to metformin alone or with rapamycin, stratified by prior treatment with FOLFIRINOX. Metformin +/ rapamyc
An exploratory study of metformin and rapamycin as maintenance therapy
Volume 11, Number 21 of Oncotarget reported that eligible patients with stable or responding mPDA after 6 months on chemotherapy were randomized 1:1 to metformin alone or with rapamycin, stratified by prior treatment with FOLFIRINOX. Metformin +/ rapamyc
New model shows how cells that cause liver cancer are created
Scientists show in-vivo and in-vitro how liver cancer stem cells are born, solving a central scientific mystery in this field
Study unveils many ways carcinogens trigger development of breast cancer
Findings provide roadmap for regulators to identify harmful chemicals that increase breast cancer risk
New model shows how cells that cause liver cancer are created
Scientists show in-vivo and in-vitro how liver cancer stem cells are born, solving a central scientific mystery in this field