English
Arabic
Chinese (Simplified)
Dutch
Esperanto
French
German
Greek
Italian
Japanese
Korean
Portuguese
Russian
Spanish
UrduThe University of Texas at El Paso will undertake potentially transformative research on how specific risk factors promote pancreatic cancer development with support from a $1 million grant from the National Institutes of Health’s National Cancer Institute.
Tag: Cancer Research
Fred Hutch at AACR: New targets for cancer therapies, experts available in diversity and cancer screening tests — and Fred Hutch’s Philip Greenberg becomes AACR president
Experts from Fred Hutchinson Cancer Center will present their latest findings on targets in RIT1-driven cancers, ROR1 CAR T-cell immunotherapy, interplay of the microbiome and genetics in colorectal cancer and more at the annual meeting of the American Association for Cancer Research, to be held April 14-19 in Orlando, Florida.
Healthy lifestyle associated with reduced mortality risk in childhood cancer survivors
St. Jude Children’s Research Hospital researchers found childhood cancer survivors have higher mortality than the public, but survivors with a healthy lifestyle and fewer heart disease risk factors had lower risk.
Five Researchers Awarded Pilot Project Funding
Institutional Research Grants provide important financial support for new treatments and discovering valuable genetic information. This year’s grants fund the development of a new skin cancer detection and treatment device, as well as studies that analyze the relationship between cancer treatment and mental health, how cells detect and repair broken DNA, how metabolism affects cancer cells, and the possible link between leukemia, inflammation, and aging.
New Review Reveals the Critical Role of Progranulin in Cancer
A recent review paper published in the journal Cancers highlights the important role of the growth factor progranulin in the initiation and progression of cancer.
SLAS Discovery Highlights Protocols in Drug Discovery for March Special Issue
The March special issue of SLAS Discovery deviates from its traditional focus on assay technology, disease area or molecular target to introduce and explore protocol articles – the newly accepted article type for outlining detailed scientific methods and procedures.
Sanford Burnham Prebys researchers awarded $2.6M to discover pancreatic cancer drugs
Cosimo Commisso, Ph.D., and Susanne Heynen-Genel, Ph.D., have received a grant from the National Cancer Institute (NCI) to advance a new treatment approach for pancreatic cancer.
Boosting the effects of a particular microRNA may benefit patients with cervical cancer
Dysregulation of microRNAs, which are molecules involved in controlling gene expression, can promote tumor formation and progression. A study in The FASEB Journal found that the miR-145 microRNA can suppress the growth of cervical cancer cells.
Can ChatGPT be Counted On?
Chatbots and artificial intelligence are increasingly becoming more popular to answer questions about health. Researchers studied one of these resources, ChatGPT, to provide incredibly valuable and well-timed insights into the capabilities and limitations of artificial intelligence in the context of cancer-related information. Are people with cancer and their caregivers getting accurate answers?
Mining the Gap
More and more students are graduating with their bachelor’s degrees and taking a gap year, a period of time before jumping into a postgraduate program. A new grant from the American Cancer Society will help the UNM Comprehensive Cancer Center introduce these students to scientific research.
UAH alumnus Michael Wicks inducted into Alabama Engineering Hall of Fame
Michael Wicks (MSE, Mechanical Engineering, ’94), is one of six honorees inducted in this year’s Alabama Engineering Hall of Fame on Feb. 25 at the Renaissance Montgomery Hotel and Spa. Wicks’ career has been devoted to providing innovative engineering and technical services to the nation’s defense, both as a United States Army civilian and as a private contractor for the Department of Defense.
Neutrons reveal how the spider lily preys on cancer, preserves healthy cells
A scientific instrument at the Department of Energy’s Oak Ridge National Laboratory could help create a noninvasive cancer treatment derived from a common tropical plant. Pancratistatin is a chemical compound found in the spider lily, a native Hawaiian flower. Unlike traditional treatments, it kills cancer cells while keeping healthy cells intact.
Research Highlights for February 2023
Read how researchers discovered genetic markers that hinder pancreatic cancer treatment and mutations that increase sarcoma risk. Then learn how artificial intelligence is helping predict prostate cancer outcomes and see how a new clinical trial looks at less-invasive breast cancer treatments. Finally, find out how a new grant could help veterans get the cancer care they need.
Cancer stage and receptor status indicate a breast cancer survivor’s risk of recurrence
New research indicates that for patients with breast cancer, the cancer’s stage and receptor status can help clinicians predict whether and when cancer might recur after initial treatment.
UChicago Medicine-led team selected for the 2022 Michael & Lori Milken Family Foundation-PCF Challenge Award to develop novel immunotherapy approaches in advanced prostate cancer
The Prostate Cancer Foundation (PCF) has awarded a $1 million grant to a renowned specialist at the University of Chicago Medicine Comprehensive Cancer Center.
AI improving digestive cancer diagnosis, but data-sharing obstacles remain
Artificial intelligence is helping to deliver earlier and better diagnoses of digestive cancers, but many challenges remain to widespread clinical application, not least limited sharing of medical imaging data between hospitals, and lack of standardization of protocols for medical imaging for AI, a group of researchers has concluded after a comprehensive survey of recent applications of the technology to these most deadly of cancers.
National Comprehensive Cancer Network Updates Annual Conference with New In-Person Venue, Hybrid Format, Expert-Led Sessions, Highlighted Research Perspectives, and Small-Group Conversations
NCCN 2023 Annual Conference featuring more than a thousand worldwide oncology professionals will present new research findings, latest NCCN Guidelines updates, and best practices for achieving quality cancer care delivery, in Orlando and online March 31—April 2, 2023. Visit NCCN.org/conference for more.
Genes reveal kidney cancer’s risk of recurrence
A decade-long international study into kidney cancer has shown that doctors can predict the likelihood of a patient’s disease returning by looking at DNA mutations in their tumours.
U.S. Study of Intravenous Mistletoe Extract to Treat Advanced Cancer
Researchers at the Johns Hopkins Kimmel Cancer Center completed what is believed to be the first phase I trial of intravenous Helixor M in the U.S. aimed at determining dosing for subsequent clinical trials and to evaluate safety.
Three Talented Researchers Recognized as Endowed Chairs
Huntsman Cancer Institute is proud to announce Brad Cairns, PhD, as the inaugural recipient of the Jon M. Huntsman Presidential Endowed Chair in Cancer Research given by the 2018 Utah State Legislature. In addition, Aik Choon Tan, PhD, was named the Jon and Karen Huntsman Presidential Professor in Cancer Research and Alana Welm, PhD, received a five-year extension as the Ralph E. and Willia T. Main Presidential Endowed Chair in Cancer Research.
MD Anderson receives nearly $19.4 million in CPRIT funding
The University of Texas MD Anderson Cancer Center today was awarded 15 grants totaling $19.38 million from the Cancer Prevention and Research Institute of Texas (CPRIT) in support of cancer research projects across the institution.
MD Anderson and Xilis announce strategic collaboration to advance novel technology and accelerate therapeutic development
MD Anderson and Xilis announced a strategic collaboration to deploy Xilis’ proprietary MicroOrganoSphere technology in support of preclinical research to accelerate the development of novel cancer therapies.
Jaime Merchán, M.D., Named a Translational and Clinical Oncology Research Program Co-Leader
Jaime Merchán, M.D., is the new Translational and Clinical Oncology Research Program co-leader at Sylvester Comprehensive Cancer Center, part of UHealth – University of Miami Health System.
Multiplication on, multiplication off: Targeting an enzymatic switch to develop oncology drugs
Interdisciplinary research highlighted lipid-protein interaction as a new avenue for oncology drug development, demonstrating its functionality by designing small molecule-based inhibitors to target acute myeloid leukemia.
Women in Medicine: Dr. Priyamvada Rai to Co-lead Tumor Biology Research Program
Priyamvada Rai, Ph.D., is the new Tumor Biology Research Program co-leader at Sylvester Comprehensive Cancer Center, part of UHealth – University of Miami Health System.
Sylvester Comprehensive Cancer Center Scientists, Collaborators Develop Powerful AI Algorithm to Gain New Insights into Deadly Glioblastoma
(MIAMI, FL, EMBARGOED UNTIL FEB. 2, 2023 AT 11 A.M. EST) — Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, collaborating with international researchers, have developed a sophisticated AI algorithm that performs advanced…
Boosting anti-cancer antibodies by reducing their grip
New research from the Centre for Cancer Immunology at the University of Southampton, published ahead of World Cancer Day (4 February), has shown that changing how tightly an antibody binds to a target could improve treatments for cancer.
Tumor microbiome linked to immunotherapy success in sarcoma patients
A new UC Davis study reveals the interaction between tumor microbiome and the immune system may be the secret to improving outcomes for sarcoma patients.
Long-term trajectories of physical function decline in women with, without cancer
About The Study: Survivors of cancer experienced accelerated declines in physical function after diagnosis, and physical function remained below that of age-matched controls even years later. Patients with cancer may benefit from supportive interventions to preserve physical functioning. Authors: Elizabeth M. Cespedes…
An Unprecedented Look at Colorectal Cancer
Researchers are building detailed maps of colorectal cancer to better understand the dynamics of the disease
Certain gene signaling rewires tumors after immunotherapy
Researchers from the University of Michigan Rogel Cancer Center have found a mechanism for why a subset of patients’ tumors grow, rather than shrink, when faced with immunotherapy.
Multimodal Sequencing Achieves High-Quality Results from Small Volumes of Frozen Tumor Specimens
Columbia researchers invent a multimodal sequencing technique that achieves high-quality results from small volumes of frozen tumor specimens–the ability to study cancer tissues archived in biobanks should increase the number and variety of tumor samples available for scientific analysis and advance the discovery of biomarkers and drug targets.
Dana-Farber researcher awarded Victoria Mock New Investigator Award
Rachel Pozzar, PhD, RN, a nurse scientist in the Phyllis F. Cantor Center for Research in Nursing and Patient Care Services at Dana-Farber Cancer Institute and an instructor in medicine at Harvard Medical School, has been awarded the 2023 Oncology Nursing Society’s (ONS) Victoria Mock New Investigator Award.
Using machine learning to predict brain tumor progression
Researchers at the University of Waterloo have created a computational model to predict the growth of deadly brain tumours more accurately.
Triple-drug therapy for post-transplant management of multiple myeloma
Promising results from an ongoing clinical trial a three-drug treatment may improve survival in patients with newly diagnosed multiple myeloma who have undergone preliminary treatment followed by a stem cell transplant.
Machine Learning-Triggered Reminders Improve End-of-Life Care for Patients with Cancer
Electronic nudges delivered to health care clinicians based on a machine learning algorithm that predicts mortality risk quadrupled rates of conversations with patients about their end-of-life care preferences, according to the long-term results of a randomized clinical trial published by Penn Medicine investigators in JAMA Oncology today.
Oncotarget | The role of pyrethroid derivatives in autophagy and apoptosis crosstalk signaling and potential risk for malignancies
A new research paper was published in Oncotarget’s Volume 13 on December 17, 2022, entitled, “The role of pyrethroid derivatives in autophagy and apoptosis crosstalk signaling and potential risk for malignancies.”
Nearly half of deaths for 12 cancers in California due to tobacco, higher than previously reported
A new study looks at cancer deaths in California due to tobacco, sounding the alarm regarding the tragic loss of life caused by tobacco addiction
Novel Drug Shows Early Promise in Treating Multiple Myeloma
A first-of-its-kind drug known as modakafusp alfa has shown early potential in combating multiple myeloma, a form of bone marrow cancer, in a study presented by researchers from the University of Pennsylvania’s Abramson Cancer Center at the 2022 American Society of Hematology (ASH) Annual Meeting (Abstract 565).
Penn Medicine Researchers Present Advance in Re-Treatment with CAR T Therapy
Researchers from the University of Pennsylvania’s Abramson Cancer Center presented preliminary results of an ongoing Phase I clinical trial demonstrating successful re-treatment with CAR T cell therapy for patients whose cancers relapsed after previous CAR T therapy at the 2022 American Society of Hematology (ASH) Annual Meeting (Abstract 2016).
P53 could be key to therapies for salivary gland cancer
Researchers at the University of Michigan Rogel Cancer Center and School of Dentistry found that certain drugs can change the fundamental makeup of cancer stem cells in mouse models of mucoepidermoid carcinoma – a lethal form of salivary gland cancer that currently has no treatment options. These results appeared in Clinical Cancer Research.
Sylvester Comprehensive Cancer Center Receives Approval to Build World-Class Myeloma Research Institute
The Myeloma Research Institute’s launch follows many important accomplishments by C. Ola Landgren, M.D., Ph.D. and his team, who are dedicated to fulfilling a promise of providing the best cancer care to myeloma patients. Florida is among the states with the highest rates of new myeloma diagnoses in the U.S., with 7.9 cases diagnosed in every 100,000 of the state’s residents.
Liver cancer study encourages caution with certain gene therapies
A newly discovered link between protein misfolding and liver cancer could help improve gene therapy for hemophilia.
How Metastatic Cancer Causes Leaky Blood Vessels
In APL Bioengineering, researchers examine the local communication between endothelial cells and tumors cells and its effects on endothelial cell orientation. The approach uses co-cultured human umbilical vein endothelial cells and breast epithelial tumor cell lines to simulate the tumor-endothelial interaction. The group found the clockwise chirality of the hUVECs was less affected by local hormone signaling and more so by direct physical contact with tumor cells. Specific proteins on the tumor cell binding to others on endothelial cells appeared to play a role in changing the clockwise chirality of hUVECs.
Space and time influence G-protein coupled receptor interactions
By simulating molecular dynamics, scientists from St. Jude Children’s Research Hospital revealed how the selectivity or promiscuity of GPCR coupling relies on the location and duration of intermolecular interactions.
More frequent CT scans not associated with improved outcomes after lung cancer surgery
A new study by researchers at Washington University School of Medicine in St. Louis found that undergoing more frequent computed tomography (CT) scans was not associated with improved outcomes following lung cancer surgery. Less frequent CT scans may reduce health-care costs, patient anxiety.
Johns Hopkins Researchers Design ‘Prodrug’ That Targets Cancer Cells’ Big Appetite for Glutamine, Leaving Healthy Cells Unharmed
Newly published study in mice show augmented drug eliminates cancer cells without causing toxicity.
Scientists uncover potential ‘electrical language’ of breast cancer cells
New research has found variable voltages in the membranes of breast cancer cells, revealing clues about how they grow and spread.
NCCN Announces Funding for Bladder Cancer Research Projects, in Collaboration with Pfizer and EMD Serono
The National Comprehensive Cancer Network’s Oncology Research Program selects projects focused on improving patient care and outcomes in locally advanced or metastatic bladder cancer.
DNA barcoding reveals cancer cells’ ability to evade the immune system
Some cancer cells can deploy parallel mechanisms to evade the immune system’s defences as well as resist immunotherapy treatment, according to a new study from the Garvan Institute of Medical Research.