English
Arabic
Chinese (Simplified)
Dutch
Esperanto
French
German
Greek
Italian
Japanese
Korean
Portuguese
Russian
Spanish
UrduNew article assesses natural language computer applications in health care
Tag: Bioinformatics
A few common bacteria account for majority of carbon use in soil
Just a few bacterial taxa found in ecosystems across the planet are responsible for more than half of carbon cycling in soils. These new findings, made by researchers at Northern Arizona University and published in Nature Communications this week, suggest…
NIH grant boosts computational search for cancer drugs
Computer scientist Lydia Kavraki and team developing toolkit to model protein-ligand interactions
How basic physics and chemistry constrain cellular functions in primitive and modern cells
A long-standing basic question in biology relates to how life satisfies the fundamental constraints put on it by physics and chemistry. Darwin’s warm pond hypothesis for the origin of primordial cells is a familiar one. Advances have been made in…
Measuring gene expression changes over time may help predict T1D diabetes progression
An international research team, including the University of South Florida Health Informatics Institute, created and validated a predictive model with potential for early monitoring of infants at risk for type 1 diabetes
From meat-production to urinary tract infections
Epidemiological study revealed that Staphylococcus saprophyticus causing urinary tract infections can have origin in food
Sensing what plants sense: Integrated framework helps scientists explain biology and predict crop performance
AMES, Iowa – Scientists have invested great time and effort into making connections between a plant’s genotype, or its genetic makeup, and its phenotype, or the plant’s observable traits. Understanding a plant’s genome helps plant biologists predict how that plant…
The 8th International Horticulture Research Conference Announcement
To showcase the latest achievements and research progress in the field of horticulture, and promote communication and cooperation among world experts, the 8th International Horticulture Research Conference will be held from July 20 to 22, 2021 in Nanjing, China, and…
“Mexican variant” and monitoring actions of SARS-CoV-2 genome
A research group of the Department of Pharmacy and Biotechnology of the University of Bologna analyzed more than one million SARS-CoV-2 genome sequences. This analysis led to the identification of a new variant that, over the past weeks, has been…
Computer simulations visualize in atomic detail how DNA opens
Researchers from the Hubrecht Institute in Utrecht (The Netherlands) and the Max Planck Institute for Molecular Biomedicine in Münster (Germany) used computer simulations to reveal in atomic detail how a short piece of DNA opens while it is tightly wrapped…
Cancer-promoting Ras protein exists in a pair within cells
Researchers from Bochum and Osnabrück have gained new insights into the structure of the Ras protein, which acts as a molecular switch for cell growth and is involved in the development of cancer. With the help of fluorescence markings, they…
Hi-CO unravels the complex packing of nucleosomes
High-resolution genome structural analyses combined with large-scale simulations show the arrangements of the genome’s spool-like structures affecting gene expression
The evolutionary fates of supergenes unmasked
While the term “supergene” may bring to mind the genetic hocus-pocus of Peter Parker’s transformation into Spiderman, supergenes are actually fairly common phenomena in the realm of biology. A supergene refers to a genomic region containing multiple genes or genetic…
Elucidating how the production of antibodies is regulated, one cell at a time
A study coordinated by Luís Graça, principal investigator at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and Professor at the Faculty of Medicine of the University of Lisbon (FMUL) used lymph nodes, tonsils and blood, to show…
Researchers develop technique to functionally identify and sequence soil bacteria one cell at a time
Researchers from the Single-Cell Center at the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences have developed a technique to sort and sequence the genome of bacteria in soil one bacterial cell at a…
Key early steps in gene expression captured in real time by CSU researchers
Capturing how RNA polymerase enzymes kick off transcription
SFU and UBC researchers collaborate to understand the role of caveolin-1 in cancer
SFU computing science professor Ghassan Hamarneh is using his medical imaging analysis expertise to help UBC researchers understand the role of caveolin-1 (CAV1) in certain cancer types. CAV1 is a protein associated with poor outcomes in aggressive breast and prostate…
Scientists call for international investment to tackle major wheat losses
Urgent investment in new tools is needed to address major global losses of wheat crops which cost £22 billion per year. Leading scientific experts are calling for governments around the world to come together and fund a new international research…
Real-world flight data shows continued need for social distancing
REYKJAVIK, Iceland 26 May 2021 – Current vaccination programmes alone will have a limited effect in stopping the second wave of COVID infections in the US, according to a study conducted by scientists from Reykjavik University, University of Lyon, University…
Raised buildings may help reduce malaria transmission in Africa
There is growing evidence that house design can decrease the force of malaria infection. The world’s most deadly assassin is Africa’s malaria mosquito: Anopheles gambiae. In 2019, the World Health Organisation estimated that malaria killed 386,000 people in sub-Saharan Africa,…
Data from smartwatches can help predict clinical blood test results
Long-term data gathered from wearables can quicky indicate illness and other abnormalities in a patient’s health
Newly discovered enzymes are not heavy metal fans
Researchers at Tsukuba University discover a new group of carbonic anhydrase enzymes that do not require any metal ions for their activity, which improves our knowledge of the global carbon cycle and may be applicable to artificial photosynthesis
Accurate evaluation of CRISPR genome editing
Researchers from IDC Herzliya and Bar-Ilan University develop a novel software tool to quantify potential CRISPR-induced errors
Virus infection cycle revealed in dynamic detail
A critical process in the infection cycle of viruses has been revealed for the first time in dynamic detail using pioneering plant-based technology. Evidence about the process of virus maturation revealed in the research could help us develop new methods…
New AI-based tool can find rare cell populations in large single-cell datasets
MD Anderson researchers have developed a first-of-its-kind AI tool to identify rare groups of biologically important cells from the noise of large, complex single-cell datasets. The new tool, called SCMER, can help reserachers gain new insights across many applications.
Technique uses fluctuations in video pixels to measure energy use of developing embryos
Scientists have made a major breakthrough in the study of embryonic development and how it can be impacted by external factors such as climate change. Researchers at the University of Plymouth have developed a cutting edge technique which enables them…
A peptide that allows cannabis-derived drugs to relieve pain without side effects
Scientists from the Proteomics and Protein Chemistry Research Group and the Neuropharmacology-Neurophar Laboratory have developed a peptide which is an ideal candidate for reducing the cognitive side effects of pain treatment with cannabis derivatives.
Global acceleration in rates of vegetation change
Wherever ecologists look, from tropical forests to tundra, ecosystems are being transformed by human land use and climate change. A hallmark of human impacts is that the rates of change in ecosystems are accelerating worldwide. Surprisingly, a new study, published…
New AI-based tool can find rare cell populations in large single-cell datasets
Computational approach enables analysis of meaningful data that otherwise may be lost in the noise
Modeling can predict mutation “hotspots” and antibody escapers in SARS-CoV-2 spike protein
Study identifies structural basis of spike protein mutations with stronger binding and antibody resistance, which may explain transmissibility of new COVID-19 variants
Long search finds grain of hope in the glume
Researchers have found the elusive genetic element controlling the elongated grains and glumes of a wheat variety identified by the renowned botanist Carl Linnaeus more than 250 years ago. The findings relating to Polish wheat, Triticum polonicum, could translate into…
Epigenetics study draws link between hatchery conditions and steelhead trout fitness
PULLMAN, Wash. – Alterations in the epigenetic programming of hatchery-raised steelhead trout could account for their reduced fertility, abnormal health and lower survival rates compared to wild fish, according to a new Washington State University study. The study, published May…
New model helps predict heart attacks in high-risk patients
Researchers have described a new approach to analysing the forces at play behind diseased heart vessels, which could help cardiologists predict heart attacks in patients
When one become two: Separating DNA for more accurate nanopore analysis
A new software tool developed by Earlham Institute researchers will help bioinformaticians improve the quality and accuracy of their biological data, and avoid mis-assemblies. The fast, lightweight, user-friendly tool visualises genome assemblies and gene alignments from the latest next generation…
Changes in proteins play important role in aging kidneys
Researchers have shown that examining both protein changes and the transcription of genes in kidneys provides a more complete picture of the aging process in these organs
Why does heart scarring cause abnormal rhythms in some people but not others?
People with stroke without atrial fibrillation have the same heart scar tissue as those with atrial fibrillation but may be lacking the triggers that cause heart rhythm disorders
UNC Charlotte researchers analyzed the host origins of SARS-CoV-2 and other coronaviruses
Coronavirus (CoVs) infection in animals and humans is not new. The earliest papers in the scientific literature of coronavirus infection date to 1966. However, prior to SARS-CoV, MERS-CoV, and SARS-CoV-2, very little attention had been paid to coronaviruses. Suddenly, coronaviruses…
Speeding new treatments
UNM team creates powerful computational tool to help researchers rapidly screen molecules for anti-COVID properties
Unlocking herbaria biodiversity using a QR code sampling-to-sequencing workflow
Within the past decade, next-generation sequencing technologies have revolutionized the way in which genetic data are generated and analyzed. In the field of phylogenetics, this has meant that researchers are rapidly reconstructing the tree of life, a goal that biologists…
Brotman Baty Institute working with Illumina and GeneDx on whole-genome sequencing study
Supporting families of children with developmental differences
TBI: A new roadmap for advancing personalized treatment solutions
First of six publications reports on new tool to identify patient subgroups that enable personalized care
Structure gives insight into how plants keep their “mouths” shut
Stomata, formed by a pair of kidney-shaped guard cells, are tiny pores in leaves. They act like mouths that plants use to “eat” and “breathe.” When they open, carbon dioxide (CO 2 ) enters the plant for photosynthesis and oxygen…
VR visualization supports research on molecular networks
A new VR platform enables the display of huge amounts of data. This can be helpful in the study of rare genetic defects, among other things.
Damon Runyon Cancer Research Foundation names 2021 Quantitative Biology Fellows
Three cutting-edge scientists will apply computational approaches to cancer research
Study reveals roadmap of muscle decline with age
A comprehensive roadmap of muscle decline with age in mice reveals possible new targets for treatments, including the molecule Klotho
“Molecular Tomographer” algorithm maps gene expression in space
As we accumulate more and more gene-sequencing information, cell-type databases are growing in both size and complexity. There is a need to understand where different types of cells are located in the body, and to map their gene expression patterns…
CityU biologists discover super-enhancers that switch on breast cancer genes
Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the major treatment option, but the clinical result is unsatisfactory. A research team led by biologists at City University of Hong…
Physicists develop theoretical model for neural activity of mouse brain
The new model may have applications for studying and predicting a range of dynamical systems
Two research projects to be receive funds from Samsung Science & Technology Foundation
DGIST announced that Prof. June.M. Kwak, and Prof. Chang-Hee Cho are selected for the research funding program sponsored by ‘Samsung Science & Technology Foundation’. Prof. Kwak was selected for the Basic Science Research and will be carrying out the project…