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UrduResearchers have developed a mathematical tool to estimate tumor-specific RNA levels from tumor samples with mixed cell types. Using this technique on thousands of samples found that higher mRNA levels are correlated with shorter survival.
Tag: Bioinformatics and Computational Biology
Fifty years of collaborative science
Scientists from around the world will come together virtually to celebrate the 50th anniversary of a key piece of the infrastructure for sharing scientific knowledge: the Protein Data Bank (PDB). The event will be hosted by the American Society for Biochemistry and Molecular Biology on May 4–5, 2021.
Fields of Breeders’ Dreams: A Team Effort Toward Targeted Crop Improvements
In Nature, a multi-institutional team including DOE Joint Genome Institute researchers has produced a high-quality reference sequence of the complex switchgrass genome. Building off this work, bioenergy researchers are exploring targeted genome editing techniques to customize the crop.
Large-scale cancer proteomics study profiles protein changes in response to drug treatments
Through large-scale profiling of protein changes in response to drug treatments in cancer cell lines, researchers at The University of Texas MD Anderson Cancer Center have generated a valuable resource to aid in predicting drug sensitivity, to understand therapeutic resistance mechanisms and to identify optimal combination treatment strategies.
Next-gen bioinformatics tool enables big data analysis without programming expertise
A new data analysis tool developed by researchers at The University of Texas MD Anderson Cancer Center incorporates a user-friendly, natural-language interface to allow biomedical researchers without specialized expertise in bioinformatics or programming languages to conduct intuitive analysis of large datasets.