Using smart bioelectronic devices to capture and release tumor cells

Metastasis is the leading cause of death in cancer, occurring when a cell leaves the primary tumour, passes into the bloodstream and lymphatic system and reaches distant organs. Non-invasive collection of these circulating tumour cells is essential for the study of cell biology, the diagnosis and prognosis in cancer research, and drug development.

Biosensors Require Robust Antifouling Protection

Some promising biosensors and medical devices work well within pristine laboratory environments but may stop working once exposed to real-world conditions. A thick layer of foulants will quickly cover biosensors, and there is no good way to revive them once they quit working. Essentially, a biosensor is only as good as its antifouling properties. In APL Materials, researchers review a variety of approaches developed to combat fouling.