English
Arabic
Chinese (Simplified)
Dutch
Esperanto
French
German
Greek
Italian
Japanese
Korean
Portuguese
Russian
Spanish
UrduPartners use AlphaFold, the AI system recognised last year as a solution to the protein structure prediction problem, to release more than 350,000 protein structure predictions including the entire human proteome to the scientific community
Tag: BIOCHEMISTRY
A rock with many perspectives
The Alum Shale of Northern Europe not only has an eventful history of formation, connected with the microcontinent Baltica, it also holds great potential as an object of investigation for future research questions. Geologists use the rock to reconstruct processes…
Investigational magnetic device shrinks glioblastoma in first-in-world human test
Houston Methodist Neurological Institute researchers from the department of neurosurgery shrunk a deadly glioblastoma tumor by more than a third using a helmet generating a noninvasive oscillating magnetic field that the patient wore on his head while administering the therapy…
New insight on the reproductive evolution of land plants
International consortium offers novel insight into the reproductive evolution of land plants, in new study published in Nature Plants
Characterized drugs show unexpected effects
Known and yet unexpected: many active substances influence the cholesterol homeostasis and thereby possibly a SARS-CoV-2 infection
Eco-friendly plastic from cellulose and water
Göttingen University researchers create new kind of environmentally friendly bioplastic with hydroplastic polymers
How does the structure of cytolysins influence their activity?
Although Enterococcus faecalis is usually an innocuous member of the bacterial community in the human gut, it can also cause several infections, including liver disorders. The bacteria produce cytolysins, which are molecules that destroy cells. In a new study, researchers…
Toxicity testing on the placenta and embryo
Drugs must be safe not just for the patients; in the case of pregnant patients, drugs must also be safe for the unborn children still in the womb. Therefore, at an early stage in the development of new medicines, candidate…
Chromosomes separation under focus
A UNIGE team has identified important regulatory mechanisms of the protein responsible for chromosome separation during cell division.
NIH Director Francis Collins and NASA Astronaut Kate Rubins to keynote joint session at ISSRDC
KENNEDY SPACE CENTER (FL), July 20, 2021 – The 2021 International Space Station Research and Development Conference (ISSRDC) will include a virtual keynote session that will feature two key science figures: National Institutes of Health (NIH) Director Dr. Francis Collins…
Coffee doesn’t raise your risk for heart rhythm problems
UCSF Cardiology researchers report no link between coffee consumption and arrhythmia
Enzyme-based plastics recycling is more energy efficient, better for environment
BOTTLE Consortium effort develops model that finds sizeable energy and carbon-saving benefits for recycling PET, a common plastic used in bottles, clothing, carpet
New study investigates formation of dangerous compounds by e-cigarettes
Scientists with the Desert Research Institute (DRI) Organic Analytical Laboratory in Reno, Nev., led by Andrey Khlystov, Ph.D., have been awarded a $1.5M grant from the National Institutes of Health (NIH) to study the formation of dangerous compounds by electronic…
SARS-CoV-2: Achilles’ heel of viral RNA
Researchers at Goethe University find small molecules as binding partners for genomic RNA of the coronavirus
A substance from Saussurea controversa will help bone tissue regeneration
Metabolic bone diseases, including osteoporosis, when bones lose their mass and become so fragile that they could be damaged while sneezing or under little stress, are called the silent epidemic of the 21st century. A person does not even know…
The international ENABLE conferences get the green light for another four years
The ENABLE international conferences, which have been held annually since 2017, are scientific gatherings organised by and for young researchers that seek to ensure the next generation of scientific leaders. Initially funded by the European Commission’s Horizon2020 programme, the first…
Mechanisms to separately regulate synaptic vesicle release and recycling
Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses
A simple compound to control complex gut microbes
Researchers at the RIKEN Center for Integrative Medical Sciences (IMS) have discovered that acetate, a major metabolite produced by some intestinal bacteria, is involved in regulating other intestinal bacteria. Specifically, experiments showed that acetate could trigger an immune response against…
How cells control mitochondria
Errors in the metabolic processes of mitochondria are responsible for a variety of diseases such as Parkinson’s and Alzheimer’s. Scientists needed to find out just how the necessary building blocks are imported into the complex biochemical apparatus of these cell…
Study shows that electronic air cleaning technology can generate unintended pollutants
As the Covid-19 pandemic raged, news reports show that sales of electronic air cleaners have surged due to concerns about airborne disease transmission. But a research team at the Georgia Institute of Technology has found that the benefits to indoor…
Artificial sweeteners enable delivery of carbon monoxide to treat organ injury
ATLANTA–An oral prodrug developed by a team of scientists led by Binghe Wang, Regents’ Professor of Chemistry at Georgia State University, delivers carbon monoxide to protect against acute kidney injury, according to a new paper published in Chemical Science .…
Add fatty acid to taste
New technology reveals single cancer cells have different appetites for fatty acids
Common COVID-19 antibiotic no more effective than placebo
UCSF outpatient study found limited effect of azithromycin on progression of disease
Bio-based coating for wood outperforms traditional synthetic options
Researchers have used lignin, a natural polymer abundant in wood and other plant sources, to create a safe, low-cost and high-performing coating for use in construction. The coating is non-toxic, hydrofobic, it retains wood’s breathability and natural roughness while being resistant to colour changes and abrasion.
Nitrogen-producing process of anammox bacterium finally uncovered
After years of research, the molecular structure of the enzyme responsible for a large part of the global nitrate and nitrogen production by bacteria has finally been uncovered. The anammox bacterium and other bacteria use this enzyme to convert toxic…
Kelp for corn? Illinois scientists demystify natural products for crops
URBANA, Ill. – Corn growers can choose from a wide array of products to make the most of their crop, but the latest could bring seaweed extract to a field near you. The marine product is just one class in…
The virus trap
Hollow nano-objects made of DNA could trap viruses and render them harmless
Quantum physics helps destroy cancer cells
Researchers have found a way to enhance radiation therapy using novel iodine nanoparticles
Metal-based molecules show promise against the build-up of Alzheimer’s peptides
In lab tests, Imperial researchers have created a metal-based molecule that inhibits the build-up of a peptide associated with Alzheimer’s disease. A peptide is a fragment of a protein, and one of the key hallmarks of Alzheimer’s disease is the…
Hydrogel composite developed to help protective gear rapidly degrade toxic nerve agents
Scientists at Northwestern University in Evanston, Illinois have developed a hydrogel integrated with zirconium-based robust metal-organic frameworks (MOFs) that rapidly degrades organophosphate-based nerve agents used in chemical warfare. Unlike existing powdered MOF adsorbents, this hydrogel composite does not require added…
Role of subnuclear NSrp70 in immunity-studied at Gwangju Institute of Science & Technology
Scientists report that the alternative-splicing regulator NSrp70 influences immune T cell development
Oldest fossils of methane-cycling microbes expand frontiers of habitability on early Earth
A team of international researchers, led by the University of Bologna, has discovered the fossilised remains of methane-cycling microbes that lived in a hydrothermal system beneath the seafloor 3.42 billion years ago. The microfossils are the oldest evidence for this…
Synthesis of one of the most abundant organic lipids elucidates its structure
Crenarchaeol is a large, closed-loop lipid that is present in the membranes of ammonium-oxidizing archaea, a unicellular life form that exists ubiquitously in the oceans. In comparison to other archaeal membrane lipids, crenarchaeol is very complex and, so far, attempts…
New research identifies key set of signals that control mucus production in the lung
Signals may offer targets for limiting mucus production in lung disease
Microcrystal electron diffraction supports a new drug development pipeline
CAMBRIDGE July 13, 2021 – To date, solving structures of potential therapeutics using X-ray diffraction (XRD) has been an assumed, pivotal step in the drug development process. But a recent paper by a team of researchers led by NanoImaging Services…
Mechanical stimuli significantly influence organ growth
Organoids help understand the complex interactions of cells and tissue
Remarkable new insights into the pathology of Usher syndrome
Usher syndrome 1G protein SANS regulates the splicing of genes, particularly those linked to Usher syndrome
Getting to the bottom of all life: Visualizing a protein key to enabling
Scientists reveal the exact process behind the upkeep of one of the cellular components where
Researchers: Let crop residues rot in the field — it’s a climate win
Plant material that lies to rot in soil isn’t just valuable as compost. In fact, agricultural crop residue plays a crucial role in sequestering carbon, which is vital for reducing global CO2 emissions.
Brain injury lab receives additional federal funding to boost research
UC Riverside postdoc and graduate students are recipients of new awards
Dying cells protect their neighbors to maintain tissue integrity
Cells undergoing cell death protect their neighbors to maintain tissue integrity
Efficient genetic engineering platform established in methylotrophic yeast
Pichia pastoris (syn. Komagataella phaffii ), a model methylotrophic yeast, can easily achieve high density fermentation, and thus is considered as a promising chassis cell for efficient methanol biotransformation. However, inefficient gene editing and lack of synthetic biology tools hinder…
Computer-assisted biology: Decoding noisy data to predict cell growth
Tokyo, Japan – Scientists from The University of Tokyo Institute of Industrial Science have designed a machine learning algorithm to predict the size of an individual cell as it grows and divides. By using an artificial neural network that does…
NIST uses method to understand the molecular underpinnings of a disease affecting corals
Coral reefs are a favorite spot for scuba divers and are among the world’s most diverse ecosystems. For example, the Hawaiian coral reefs, known as the “rainforests of the sea,” host over 7,000 species of marine animals, fishes, birds and…
Using mice to open the way to prevent blocked arteries
Researchers from Tokyo Medical and Dental University (TMDU) identify pathways that link a high-fat diet to atherosclerosis in mice Tokyo, Japan – It’s long been known that a high-fat diet can lead to clogged arteries, but we have only recently…
Newborn screening for epilepsy in sight through the discovery of novel disease biomarkers
The door has finally opened on screening newborn babies for pyridoxine-dependent epilepsy (PDE), a severe inherited metabolic disorder. This screening promises to enable better and earlier treatment of the disease. To identify new biomarkers that can be used in the…
Hybrid enzyme catalysts synthesized by a de novo approach for expanding biocatalysis
The two major challenges in industrial enzymatic catalysis are the limited number of chemical reaction types that are catalyzed by enzymes and the instability of enzymes under harsh conditions in industrial catalysis. Expanding enzyme catalysis to a larger substrate scope…
More ancestral enzyme
Molecular evolution of enzyme beyond recruit hypothesis
To predict underwater volcano eruptions, scientist looks at images from space
A new study monitored satellite images to obtain sea discoloration data as a novel indicator in detecting if an underwater volcano’s eruption is imminent.