Dozens of potential new antibiotics discovered with free online app

CHAMPAIGN, Ill. — A new web tool speeds the discovery of drugs to kill Gram-negative bacteria, which are responsible for the overwhelming majority of antibiotic-resistant infections and deaths. The tool also offers insights into discrete chemical changes that can convert…

CSU lands $1.2 million in NIH funding to advance work on a new tuberculosis vaccine

A team of researchers in the Department of Microbiology, Immunology and Pathology at Colorado State University aim to advance what is known about the complex immune response necessary to prevent tuberculosis disease. The university was recently awarded a $1.2 million…

How Crohn’s disease-associated bacteria tolerate antibiotics

Bacteria associated with Crohn’s disease rely on multiple stress responses to survive, multiply, and tolerate antibiotics within white blood cells called macrophages, according to a study published November 14 in the open-access journal PLOS Pathogens by Olivier Espéli of the…

How Crohn’s disease-associated bacteria tolerate antibiotics

Bacteria associated with Crohn’s disease rely on multiple stress responses to survive, multiply, and tolerate antibiotics within white blood cells called macrophages, according to a study published November 14 in the open-access journal PLOS Pathogens by Olivier Espéli of the…

Wildlife in Catalonia carry bacteria resistant to antimicrobials used in human health

Antibiotic resistance has become a global health problem due to decades of misuse of these drugs in both, human and veterinary medicine. Nowadays the prevalence of multi-drug resistant bacteria in humans, domestic animals and livestock has increased, hindering the finding…

University of Florida scientists advance citrus greening research efforts

Citrus greening, a devastating disease, has reduced Florida citrus production by 70%, according to most accounts. Efforts to develop disease control methods have been stymied because scientists have been unable to culture and experimentally manipulate the causal bacterial pathogen, Candidatus…

Wildlife in Catalonia carry bacteria resistant to antimicrobials used in human health

Antibiotic resistance has become a global health problem due to decades of misuse of these drugs in both, human and veterinary medicine. Nowadays the prevalence of multi-drug resistant bacteria in humans, domestic animals and livestock has increased, hindering the finding…

University of Florida scientists advance citrus greening research efforts

Citrus greening, a devastating disease, has reduced Florida citrus production by 70%, according to most accounts. Efforts to develop disease control methods have been stymied because scientists have been unable to culture and experimentally manipulate the causal bacterial pathogen, Candidatus…

Potential vitamin and Alzheimer’s drug produced in yeast

Ergothioneine is a natural amino acid with antioxidative properties. It prevents cellular stress, which can lead to brain diseases, neurological damage and cancer. In rats and roundworms, research shows that ergothioneine has promising effects in preventing neurodegenerative diseases such as…

Salmonella — how the body fights back

New research from the University of East Anglia shows how the human body powers its emergency response to salmonella infection. A study, published today in the journal PNAS , reveals how blood stem cells respond in the first few hours…

Potential vitamin and Alzheimer’s drug produced in yeast

Ergothioneine is a natural amino acid with antioxidative properties. It prevents cellular stress, which can lead to brain diseases, neurological damage and cancer. In rats and roundworms, research shows that ergothioneine has promising effects in preventing neurodegenerative diseases such as…

Salmonella — how the body fights back

New research from the University of East Anglia shows how the human body powers its emergency response to salmonella infection. A study, published today in the journal PNAS , reveals how blood stem cells respond in the first few hours…

Study points to new weapon in fight against lethal fungi

Monash University researchers have gained insights into how nanoparticles could develop a biosensor to prevent deadly diseases contracted on medical equipment, such as catheters. Candida albicans can become a serious problem for people who are seriously ill or immune-suppressed. Researchers…

Targeted gene modification in animal pathogenic chlamydia

The human pathogenic bacterium Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen worldwide. It is estimated to infect more than 100 million people each year and is a frequent cause of infertility. Moreover, Chlamydia trachomatis also causes eye…

Shark skin microbiome resists infection

A survey of the shark skin microbiome provides the first step toward understanding the remarkable resilience of shark wounds to infection. In the wild, blacktip reef sharks are often seen bearing wounds, but they rarely exhibit obvious signs of infection…

Shark skin microbiome resists infection

A survey of the shark skin microbiome provides the first step toward understanding the remarkable resilience of shark wounds to infection. In the wild, blacktip reef sharks are often seen bearing wounds, but they rarely exhibit obvious signs of infection…

Shark skin microbiome resists infection

A survey of the shark skin microbiome provides the first step toward understanding the remarkable resilience of shark wounds to infection. In the wild, blacktip reef sharks are often seen bearing wounds, but they rarely exhibit obvious signs of infection…

A weapon to make a superbug to become more deadly

A recent research led by a scientist at City University of Hong Kong (CityU) has discovered an easily transmitted DNA piece that can make a new type of hyper-resistant and deadly superbug become hyper-virulent quickly, posing an unprecedented threat to…

Anti-arthritis drug also stops tuberculosis bacillus from multiplying in blood stem cells

Immunologist Johan Van Weyenbergh (KU Leuven) and his Belgian-Brazilian colleagues have shown that a drug used to fight arthritis also stops the process that allows the tuberculosis bacillus to infect and hijack blood stem cells. Tuberculosis (TB) may affect any…