Tag: antibody-drug conjugate

Precision Breast Cancer Trial Shows Improved Treatment by Tumor Subtype

sarah JonasResearch Results

Recent results from one of the I-SPY 2.2 study arms, published September 14, 2024 in Nature Medicine, showed that neoadjuvant treatment with the antibody-drug conjugate datopotamab–deruxtecan (Dato-DXd) in combination with the immune checkpoint inhibitor, durvalumab (Imfinzi), produced high rates of pCR in patients who have an immune breast cancer subtype as well as a subtype of triple negative cancer that would ordinarily have a high risk of recurrence.

Trastuzumab deruxtecan significantly outperforms chemotherapy for the treatment of advanced breast cancer

sarah JonasResearch Alert

A new study published in NEJM and led by global principal investigator Aditya Bardia, MD, director of Translational Research Integration at the UCLA Health Jonsson Comprehensive Cancer Center, found trastuzumab deruxtecan (T-DXd), an antibody-drug conjugate, significantly improves progression-free survival compared to…