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UrduIn a study by Yale Cancer Center, researchers report on the discovery of a common mechanism that promotes both autoimmune diseases and blood cancers, including the blood diseases Acute Lymphoblastic Leukemia (ALL), Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL).
Tag: ALL acute lymphoblastic leukemia
Researchers Discover Mechanism to Overcome Drug-Resistance in B-Cell Acute Lymphoblastic Leukemia
In a new study led by Yale Cancer Center, researchers have discovered a novel metabolic gatekeeper mechanism for leukemia. This mechanism depends on a molecule called PON2, which could lead to a new treatment for the disease. The findings were published online today in the Proceedings of the National Academy of Sciences.
Niagara Falls ‘Miracle’ Baby Beats Aggressive Leukemia After Successful CAR-T Cancer Immunotherapy in Buffalo
“She’s a bundle of joy, she’s a blessing. She’s just life.” That’s what Cariorl Mayfield of Niagara Falls, NY, says about his young daughter, Chastity, a year after she went through a complex series of therapies at the Roswell Park Oishei Children’s Cancer and Blood Disorders Program to treat the leukemia she was diagnosed with at only 5 weeks old.
Inherited genetic variant influences response to leukemia treatment for some children
St. Jude researchers showed that an inherited variant of the GATA3 gene is tied to minimal residual disease levels and response to therapy for acute lymphoblastic leukemia.
Combination therapy results in 98% response rate for some newly diagnosed leukemia patients
A study combining low-dose chemotherapy with a monoclonal antibody is effective for older patients with Philadelphia chromosome-negative ALL.