Study Highlights Importance of Cellular Substrates and Physical Environment as Determinants to Cell Migration

Article title: Bioenergetics underlying single cell migration on aligned nanofiber scaffolds

Authors: Abinash Padhi, Alexander H. Thomson, Justin B. Perry, Grace N. Davis, Ryan P. McMillan, Sandra Loesgen, Elizabeth N. Kaweesa, Rakesh Kapania, Amrinder S. Nain, David A. Brown

From the authors:“Our studies highlight the importance of cellular substrates and the physical environment as critical determinants to cellular migration. The combination of physiologically-relevant scaffolds with substrate conditions that may better reflect energy demands in vivo have provided new insight into the bioenergetics that underlie cellular migration.”

This study is highlighted as one of February’s “best of the best” as part of the American Physiological Society’s APSselect program.

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