Researchers ID New Mechanism to Promote Healing of Digestive System’s Mucus Barrier

Article title: Pharmacological HIF-1 stabilization promotes intestinal epithelial healing through regulation of α-integrin expression and function

Authors: Bridie Jane Goggins, Kyra Minahan, Simonne Sherwin, Wai S. Soh, Jennifer Pryor, Jessica Bruce, Gang Liu, Andrea Mathe, Darryl A. Knight, Jay C. Horvat, Marjorie Walker, Simon Keely

From the authors: “This study has provided insight into the role of [hypoxia inducible factor] in apha-integrin responses and function during epithelial migration and proliferation.” 

This study is highlighted as one of March’s “best of the best” as part of the American Physiological Society’s APSselect program.