Researchers ID Congenital Heart Defect Gene Variants in People of Han Chinese Ethnicity

Article title: Identification of variants of ISL1 gene promoter and cellular functions in isolated ventricular septal defects

Authors: Si-Qiang Zheng, Huan-Xin Chen, Xiao-Cheng Liu, Qin Yang, Guo-Wei He

From the authors: “This study may provide new insights into the role of the gene promoter region for a better understanding of genetic basis of the formation of [congenital heart defects] and may promote further investigations on mechanism of the formation of [congenital heart defects].”

This study is highlighted as one of September’s “best of the best” as part of the American Physiological Society’s APSselect program.