Effect of high vs. low dosage of chloroquine diphosphate on SARS-CoV-2 infection

What The Study Did:

This randomized clinical trial evaluates the safety and efficacy of two  chloroquine diphosphate dosages in patients with severe coronavirus disease 2019 (COVID-19).

Authors:

Marcus Vinícius Guimarães Lacerda, M.D., of the Fundação de Medicina Tropical Dr Heitor Vieira Dourado in Manaus, Brazil, is the corresponding author.

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Editor’s Note:

The article contains conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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About JAMA Network Open:

JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.