news, journals and articles from all over the world.
Members of the Hematologic Malignancies Program at Rutgers Cancer Institute of New Jersey examined the utilization of a low dose of oral vancomycin, a drug used at higher doses to treat established Clostridium difficile infection (CDI), as a way to prevent CDI in blood and bone marrow transplant (BMT) patients.
White blood cells are part of many immune system responses in the human body. New research shows that a specific type of those cells may cause brain cancer tissues to die – but that’s not good news, according to researchers at Penn State College of Medicine and Penn State Cancer Institute.
Three University of Michigan researchers say eye care accessibility around the globe isn’t keeping up with an aging population, posing challenges for eye care professionals over the next 30 years.
Many people are enjoying longer, healthier lives, but current retirement ages are posing challenges for both policymakers and retirees. A new study looked into whether there is potential to increase the retirement age.
Using active acoustic telemetry and sonar data, a study provides the first detailed documentation of a shallow water fish diving 450 feet deep to spawn. Prior research has shown that bonefish dive about 164 feet to spawn, but this new and unprecedented study reveals that they reached depths of 450 feet, and moved below 325 feet for two hours before spawning in a rush upward to 220 feet deep.
By analysing minute vibrations on common items caused by sound waves, a potential attacker can use a robot vacuum cleaner to retrieve audio data and capture private and sensitive information
Scientists at St. Jude Children’s Research Hospital have identified genetic variants in African American childhood cancer survivors that have implications for up-front care and long-term surveillance.
Today, during the ASH Annual Meeting and Exposition, Eunice Wang, MD, Chief of Leukemia and Director of Infusion Services at Roswell Park Comprehensive Cancer Center, is presenting data on two ongoing studies incorporating new treatment options for AML.
Older individuals are at an increased risk of developing primary central nervous system lymphoma (PCNSL). In a retrospective study of patients with newly diagnosed PCNSL, researchers at Rutgers Cancer Institute of New Jersey and colleagues used geriatric assessments to analyze detailed characteristics, treatment, and outcomes in patients across 17 academic centers.
Researchers from Rutgers Cancer Institute of New Jersey evaluated the frequency of SARS-CoV-2, the virus that causes COVID-19, on various environmental surfaces in outpatient and inpatient hematology/oncology settings located within Rutgers Cancer Institute and Robert Wood Johnson University Hospital, an RWJBarnabas Health facility. The study revealed extremely low detection of SARS-CoV-2 on environmental surfaces across multiple outpatient and inpatient oncology areas, including an active COVID-19 floor.
A new biomarker discovered by a team that includes researchers from Penn Medicine identifies patients with an aggressive form of lymphoma unlikely to respond to the targeted treatment ibrutinib.
لا يُعد التحرش الجنسي ظاهرة جديدة أو نادرة في مكان العمل، ولكن منذ بدأت حركة #MeToo (#أنا_أيضًا) في أواخر عام 2017 تقدم المزيد من الضحايا للإبلاغ عن اتهامات بالتحرش في مكان العمل، ومنها مؤسسات الرعاية الصحية.
性骚扰在工作场所并不新奇或罕见，但自2017年底#MeToo运动开始以来，更多的受害者挺身而出，举报工作场所（包括医疗机构）中的骚扰行为。
O assédio sexual não é um fenômeno novo ou raro no local de trabalho, mas desde o início do movimento #MeToo (#EuTambém) no final de 2017, mais vítimas se apresentaram para relatar alegações de assédio no trabalho, inclusive em instituições de saúde.
Researchers reporting in ACS’ Environmental Science & Technology have discovered that measuring SARS-CoV-2 in settled solids from sewage treatment plants could be a more sensitive approach than measuring the virus in wastewater flowing into the facilities.
Brief “huddles” — rather than a barrage of emails and texts about safety and risk — may be the fastest and simplest way for hospital workers to avoid communication overload as they deal with the flood of COVID-19 cases, a Baylor University researcher says.
Researchers at Washington University School of Medicine in St. Louis have found a novel form of the Alzheimer’s protein tau in the fluid surrounding the brain and spinal cord. This form of tau — known as MTBR tau — indicates what stage of Alzheimer’s a person is in and tracks with tangles of tau protein in the brain.
Knocking out a protein known to stifle T cell activation on CAR T cells using the CRISPR/Cas9 technology enhanced the engineered T cells’ ability to eliminate blood cancers.
A study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy, is a safe and effective first-line therapy for patients with high-risk large B-cell lymphoma (LBCL), a group with an urgent need for new and effective treatments.
The novel oral drug venetoclax can be safely added to standard therapies for some high-risk myeloid blood cancers and in early studies the combination shows promise of improved outcomes, say scientists from Dana-Farber Cancer Institute.
A subcutaneous injection of the immune-boosting drug teclistamab was found to be safe and elicit responses in a majority of patients with relapsed or refractory multiple myeloma.
A CAR T-cell therapy known as axicabtagene ciloleucel (axi-cel) drove cancer cells to undetectable levels in nearly 80% of patients with advanced non-Hodgkin lymphoma (NHL) in a phase 2 clinical trial, Dana-Farber Cancer Institute investigators report at the virtual 62nd American Society of Hematology (ASH) Annual Meeting.
Clonal hematopoiesis (CH) is a recently identified condition in which mutations associated with blood cancers are detected in the blood of some healthy, usually older, individuals who don’t have cancer. People with CH, while asymptomatic, have an elevated risk of developing blood cancers and other negative health outcomes, including heart attacks and strokes.
Until you or a loved one are facing treatment for a cancer diagnosis, you may not realize the cost associated with treatment and doctor visits.
A new approach to cancer therapy shows potential to transform the commonly used chemotherapy drug gemcitabine into a drug that kills cancer cells in a specialized way, activating immune cells to fight the cancer, according to a study led by Cedars-Sinai Cancer investigators.
A team of investigators at NYU Langone Health has found that once hospitalized, Black patients (after controlling for other serious health conditions and neighborhood income) were less likely to have severe illness, die, or be discharged to hospice compared to White patients.
A new study out of UChicago Medicine published December 4, 2020, in the journal JMIR Medical Informatics examines the increase in telemedicine visits due to the COVID-19 pandemic and recommends adopting policies that encourage virtual visits going forward.
The December 2020 issue of the Society of Toxicology’s official journal, Toxicological Sciences, delivers cutting-edge toxicological research in endocrine toxicology, environmental toxicology, organ-specific toxicology, and more.
As ORNL’s fuel properties technical lead for the U.S. Department of Energy’s Co-Optimization of Fuel and Engines, or Co-Optima, initiative, Jim Szybist has been on a quest for the past few years to identify the most significant indicators for predicting how a fuel will perform in engines designed for light-duty vehicles such as passenger cars and pickup trucks.
Research updates provide a strong focus on CAR-T cell therapy and small molecules to treat the most common blood cancers: leukemia, lymphoma, and myeloma
A novel Alzheimer’s disease marker—coming early in progression of the condition—could open significant new fronts of research into possible therapies
Analysis of Victorian data by the Murdoch Children’s Research Institute suggests that COVID-19 cases in schools and childcare were mainly driven by community transmission
Heart disease is the main cause of death in developed countries.
Researchers at La Jolla Institute for Immunology (LJI) have found that people with sepsis have never-before-seen particles in their blood. The scientists are the first to show that these particles, called elongated neutrophil-derived structures (ENDS), break off of immune cells and change their shape as they course through the body.
Emotions are complex phenomena that influence our minds, bodies and behaviour.
A new clinical trial offers the most compelling evidence to date that a donor stem cell transplant can improve survival rates for older patients with higher-risk myelodysplastic syndrome (MDS), Dana-Farber Cancer Institute investigators report at the virtual 62nd American Society of Hematology (ASH) Annual Meeting.
Researchers from the Institute of Biomedicine of Seville (IBIS) have presented a study carried out in the Clinical Biochemistry Service of the Virgen del Rocío University Hospital which identifies the values for six biochemical biomarkers that indicate a patient may be infected with SARS-COV-2 (COVID-19).
A combined research team from the Universities of Portsmouth and Bournemouth and Portsmouth Hospitals University NHS Trust has shown that an assessment score used to measure a patient’s severity of illness can be applied to patients with Covid-19 without modification.
Immunity passports are a means of registering whether an individual has developed immunity to COVID-19 and is therefore unlikely to either catch or spread the disease.
Researchers from the Niels Bohr Institute, University of Copenhagen have, in collaboration with Norwegian researchers in the ERC Synergy project, ICE2ICE, shown that abrupt climate change occurred as a result of widespread decrease of sea ice.
Researchers have identified factors that make children with diabetic ketoacidosis more likely to experience acute kidney injury. Analyzing data from a large, multicenter clinical trial, the researchers also found that children who experience acute kidney injury are more likely to also experience subtle cognitive impairment and demonstrate lower IQ scores, suggesting a pattern of multiple organ injury.
In a new paper in the journal Nature, BIDMC researchers shed light on the role of antibodies and immune cells in protection against SARS-CoV-2, the virus that causes COVID-19, in rhesus macaques.
The U.S. NSF’s Daniel K. Inouye Solar Telescope just released its first image of a sunspot. The telescope’s four-meter primary mirror will give the best views of the Sun from Earth throughout the next solar cycle. This image is an indication of the telescope’s advanced optics. The image is released along with the first of a series of Inouye-related articles featured in the Solar Physics Journal.
Investigators from Foundation Medicine, Inc. and Rutgers Cancer Institute of New Jersey, the state’s only National Cancer Institute-designated Comprehensive Cancer Center, examined genomic ancestry in BCL subtypes applying genomic ancestry prediction methodology to comprehensive genomic profiling data and found multiple genomic differences. Results of the study will be shared at the virtual American Society of Hematology Annual Meeting.
Results from the ProtoDUNE single-phase detector at CERN pave the way for detectors 20 times larger for the international Deep Underground Neutrino Experiment, hosted by Fermilab.
The findings of a new report suggest that integrated strategies across food production, biodiversity, climate, and diets can meet the objectives of the Paris Agreement and the Sustainable Development Goals (SDGs).
The new method could be the key to designing more efficient batteries for specific uses, like electric cars and airplanes.
UC San Diego’s nationally recognized, evidence-based Return to Learn program employs a comprehensive suite of education, monitoring, testing, intervention and notification tools that no other university is using. And the program continues to expand—including a recent introduction of weekly self-administered student testing kits, growth of the campus’s wastewater viral monitoring program and widespread use of the cellphone-based CA COVID Notify exposure notification system.
A new study by the UC Davis MIND Institute finds a connection between gestational age and ADHD in children with Down syndrome. An earlier gestational age is linked to higher ADHD symptoms later in childhood.
A team led by scientists at the University of Washington and the University of California, San Diego has discovered that cowpeas — a type of bean plant — harbor receptors on the surface of their cells that can detect a compound in caterpillar saliva and initiate anti-herbivore defenses.
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