An unexpected approach blurs the line between synthetic drug molecules and natural products, with the goal of achieving higher quality compounds for medicines
Author: sarah Jonas
DNA-like material could bring even smaller transistors
WEST LAFAYETTE, Ind. — Computer chips use billions of tiny switches, called transistors, to process information. The more transistors on a chip, the faster the computer. A material shaped like a one-dimensional DNA helix might further push the limits on…
Feds back Rice computer scientist’s security strategy
Ang Chen wins prestigious National Science Foundation CAREER Award
Creating hope in conflict: A humanitarian grand challenge selects finalists
February 10, 2020, Toronto, Canada – Three finalists were announced today for the Creating Hope in Conflict: A Humanitarian Grand Challenge Transition to Scale program. The Grand Challenge–supported by the U.S. Agency for International Development, the UK Department for International…
Summary report on small cell lung cancer research points to progress and challenges
New summary published in February issue of the Journal of Thoracic Oncology
Rifles and shotguns used more often in youth and rural suicides
The researchers say their findings, published Feb. 3 in Injury Epidemiology , suggest that adopting safety measures for rifles or shotguns may prevent suicides, particularly among young people and rural-area residents. “Our goal as clinicians at Johns Hopkins Medicine is…
Superior ‘bio-ink’ for 3D printing pioneered
Rutgers researchers are developing materials to help grow human tissues
Experimental measurement of the quantum geometric tensor using coupled qubits in diamond
The quantum geometric tensor represents a central and ubiquitous concept in quantum mechanics, by characterizing the geometric structure of the Hilbert space. It is responsible to a number of striking phenomena, such as quantum phase transitions and novel topological matters,…
Brain-wave pattern can identify people likely to respond to antidepressant, study finds
A new method of interpreting brain activity could be used in clinics to help determine the best treatment options for depression, according to a Stanford-led trial. Stanford researchers and their collaborators used electroencephalography, a tool for monitoring electrical activity in…
Oblique electrostatic inject-deposited TiO2 film leads efficient perovskite solar cells
A collaborative research team from Kanazawa University, Waseda University, and Tokai university reports a simple new approach to electrostatic layer deposition for preparing low-cost solar cells with scale-up potential.
Initial protective role of nervous system’s ‘star-shaped cells’ in sporadic motor neuron disease uncovered
Support cells in the nervous system help protect motor neurons in the early-stages of sporadic motor neuron disease, according to new research from the Crick and UCL. Motor neuron disease is a degenerative condition which destroys the nerve cells (motor…
Powering the future: Smallest all-digital circuit opens doors to 5 nm next-gen semiconductor
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Socionext Inc. have designed the world’s smallest all-digital phase-locked loop (PLL). PLLs are critical clocking circuits in virtually all digital applications, and reducing their size and improving their performance is a…
Adding sewage sludge on soils does not promote antibiotic resistance, Swedish study shows
Adding sewage sludge on soils does not promote antibiotic resistance, a study from University of Gothenburg shows. Some of the antibiotics we use end up in sewage sludge, together with a variety of antibiotic resistant bacteria present in feces. Therefore,…
Coronavirus outbreak raises question: Why are bat viruses so deadly?
Bats’ fierce immune systems drive viruses to higher virulence, making them deadlier in humans
Common medication may lower risk of ‘broken heart’ during bereavement
The increased risk of heart attack or “a broken heart” in early bereavement could be reduced by using common medication in a novel way, according to a world-first study led by the University of Sydney and funded by Heart Research…
Long-term learning requires new nerve insulation
Study in mice adds to evidence for overlooked role of myelin in long-term memory storage
Simulations identify missing link to determine carbon in deep Earth reservoirs
Understanding the Earth’s carbon cycle has important implications for understanding climate change and the health of biospheres. But scientists don’t yet understand how much carbon lies deep in the Earth’s water reservoirs — for example, in water that is under…
San Antonio researchers win $18 million contract to develop tularemia vaccine
Vaccine would be the first to protect against tularemia in the United States
Testosterone levels affect risk of metabolic disease and cancers
Having genetically higher testosterone levels increases the risk of metabolic diseases such as type 2 diabetes in women, while reducing the risk in men. Higher testosterone levels also increase the risks of breast and endometrial cancers in women, and prostate…
Investigational drugs didn’t slow cognitive decline in rare, inherited Alzheimer’s, initial analysis indicates
Top-line data reported from international trial
Triplex reduces cytomegalovirus complications by half and induces immunity in stem cell transplant
Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine . The summaries are not intended to substitute for the full articles as a source of information. This information is…
Pharmacological migraine prophylaxis shows almost no effect in children
Migraines affect not only adults but frequently also children and adolescents. Researchers from the University of Basel have concluded that in this age group, the preventive pharmacological treatment of migraine is no more effective than placebo in the long term.…
Human gut-in-a-dish model helps define ‘leaky gut,’ and outline a pathway to treatment
3D human gut organoids reveal molecular system that keeps intestinal linings sealed, demonstrate how the system breaks down and how it can be strengthened with the diabetes drug metformin
SwRI leads $18 million DOD project to develop tularemia ‘rabbit fever’ vaccine for military
SwRI collaborating with UTSA, Lovelace on drug development for intradermal delivery
Statins may lower mortality in high-risk prostate cancer patients
Statin use alone or with metformin is associated with lower prostate cancer mortality from all causes, among high-risk patients.
Researchers virtually ‘unwind’ lithium battery for the first time
An international team led by researchers at UCL has revealed new insights into the workings of a lithium battery by virtually “unrolling” its coil of electrode layers using an algorithm designed for papyrus scrolls. In a study published in Nature…
Novel melatonin receptor molecules make possible therapies to adjust biological clock
In a mouse model of jet lag, these molecules altered adjustments to light/dark cycles, potentially addressing circadian rhythm disturbances
Rare-earth element material could produce world’s smallest transistors
RESEARCH TRIANGLE PARK, N.C. — A material from a rare earth element, tellurium, could produce the world’s smallest transistor, thanks to an Army-funded project. Computer chips use billions of tiny switches called transistors to process information. The more transistors on…
New DTU research supports previous studies on global sea level rise
Using data from European satellites, a young student at DTU Space has demonstrated that the global sea level rise has accelerated over the past four decades.
Geothermal energy: Drilling a 3,000 meters deep well
Researchers from the University of Geneva have studied the seismic activity recorded during the drilling of a geothermal well and shown that it did not spark any major earthquake.
Harnessing the sun to bring fresh water to remote or disaster-struck communities
A device that takes a novel approach to removing salt from water has been developed in Bath, paving the way for small, solar-powered desalination units
Inner ‘clockwork’ sets the time for cell division in bacteria
Researchers at the Biozentrum of the University of Basel have discovered a “clockwork” mechanism that controls cell division in bacteria. In two publications, in ” Nature Communications ” und ” PNAS “, they report how a small signaling molecule starts…
Complimentary press registration available for ACR’s 2020 State of the Art Clinical Symposium
ATLANTA – The American College of Rheumatology (ACR) welcomes members of the press to write about rheumatology research presented at the State-of-the-Art Clinical Symposium (SOTA) in New Orleans on March 27-29. This year’s line-up features presentations on cancer screenings in…
It’s Iron, Man: ITMO scientists found a way to treat cancer with iron oxide nanoparticles
Scientists from ITMO University non-invasively released antitumor drug from polymer containers modified with iron oxide nanoparticles inside primary cancer cells
Model shows how to make on-farm sustainable energy projects profitable
Researchers have developed a model that could boost investment in farm-based sustainable energy projects by allowing investors to more accurately predict whether a project will turn a profit. The model improves on earlier efforts by using advanced computational techniques to…
NIH-funded clinical trial to test PrEP, dapivirine ring for safety in pregnant women
Study also to examine whether pregnant women accept, use these HIV prevention tools
Neural signature identifies people likely to respond to antidepressant medication
NIH-funded research used machine learning algorithm to predict individual treatment response
NRL-built camera provides view into sun’s polar regions
WASHINGTON — The Solar Orbiter mission will use a U.S. Naval Research Laboratory-designed and -built heliospheric camera, known as SoloHI, to provide unique perspectives and unprecedented views of the Sun’s North and South poles. The spacecraft, a NASA and European…
NASA analyzes ex-Tropical Cyclone Damien’s rainfall in Western Australia
Tropical Cyclone Damien made landfall on Feb. 9 along the northern Pilbara coast of Western Australia. On Feb. 10, the GPM or Global Precipitation Measurement mission core satellite analyzed the rainfall generated by the remnants that triggered warnings. As Damien…
NASA examines Tropical Storm Uesi’s heavy rainfall
NASA analyzed Tropical Storm Uesi’s rainfall and found moderate to heavy rainfall around the storm’s center and in a large band of thunderstorms south of the center. That heavy rainfall has triggered warnings for Vanuatu in the Southern Pacific Ocean.…
New method offers more stable, efficient electrocatalytic reactions
Approach fluidizes catalyst particles in electrolyte instead of gluing them to electrodes??
New technology could help solve AI’s ‘memory bottleneck’
Magnetic memory device is smallest demonstrated and uses record-low current
Adapting to climate change: We’re doing it wrong
Researchers, policymakers should focus on transformative strategies
Financial pressure makes CFOs less likely to blow the whistle
A recent study finds that corporate financial managers do a great job of detecting signs of potential fraud, but are less likely to voice these concerns externally when their company is under pressure to meet a financial target. “One of…
NCCN 2020 Annual Conference: Celebrating 25 years of NCCN
Evolving practices and emerging debates in cancer care
Finding a cure for Fido’s brain cancer may help us find a cure for ourselves
Cancer research using experimental models–everything from cancer cells in a dish to patient tumors transplanted in mice–has been extremely useful for learning more about the disease and how we might treat it. For some cancers, however, these models have failed…
Palliative vs. standard care for Parkinson’s disease
What The Study Did: This randomized clinical trial that included 210 patients with Parkinson disease and related disorders and 175 caregivers examined whether outpatient palliative care was associated with better patient or caregiver outcomes compared with standard care. To access…
Epigenetics: Inheritance of epigenetic marks
A study undertaken by an international team led by Ludwig-Maximilians-Universitaet (LMU) in Munich molecular biologist Axel Imhof sheds new light on the mechanisms that control the establishment of epigenetic modifications on newly synthesized histones following cell division. The classical genetic…
Creating the ideal nasal tip contour
New Rochelle, NY, February 10, 2020–The dramatic shift in how nasal tip surgery is being performed given changes in the intended goals and evolving techniques is highlighted in a Special Communication by and interview with Dean Toriumi, MD, published in…
Study: To slow an epidemic, focus on handwashing
Improving the rate of handwashing at just 10 major airports could significantly slow the spread of a viral disease, researchers estimate