Assessment of maternal, neonatal cord blood SARS-CoV-2 antibodies, placental transfer ratios

What The Study Did:


Maternally derived antibodies are a key element of neonatal immunity. This study examined the association between maternal and neonatal SARS-CoV-2-specific antibody concentrations because understanding the dynamics of maternal antibody responses to SARS-CoV-2 infection during pregnancy and subsequent transplacental antibody transfer can inform neonatal management as well as maternal vaccination strategies.

Authors:


Scott E. Hensley, Ph.D., of the University of Pennsylvania in Philadelphia, and Karen M. Puopolo, M.D., Ph.D., of the Children’s Hospital of Philadelphia, are the corresponding authors.

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(doi:10.1001/jamapediatrics.2021.0038)

Editor’s Note:

The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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