ASH announces top trainee abstracts of 2019 Annual Meeting

(WASHINGTON, November 7, 2019) – The American Society of
Hematology (ASH) is pleased to recognize the following trainees, whose
meritorious scientific abstract has received one of the awards in the

ASH Abstract


Achievement Award program portfolio

, at the 61st ASH Annual Meeting,
December 7-10 in Orlando.

Trainees and trainee led research are vital to the advancement of the field of hematology. ASH, recognizing the impact of research conducted by the next generation of leaders in the field, has a comprehensive award program dedicated to recognizing commendable science submitted to the ASH Annual Meeting.

“I am thrilled to acknowledge these talented early-career researchers for their outstanding contributions in hematology,” said ASH President Roy Silverstein, MD, of the Medical College of Wisconsin in Milwaukee. “Being able to present their work at the annual meeting is an incredible opportunity for them to gain recognition for their hard work and grow in their careers.”


The 2019 Outstanding Abstract Achievement Award
recipients are:


Undergraduate Student

Stacy B. Kiven, BS

University of Minnesota, Minneapolis, MN

Abstract

76


Calpain-1 Contributes to Pain and
Organ Damage in Sickle Cell Disease


Medical Student

Hrishikesh Srinagesh, BA

Icahn School of Medicine at Mount Sinai, New York, NY

Abstract

367


The MAGIC Algorithm Probability
(MAP): A Novel Laboratory Biomarker for the Response to Treatment of Acute
Graft-Versus-Host Disease


Graduate Student

Melanie Castro-Mollo, MD

Icahn School of Medicine at Mount Sinai, New York, NY

Abstract

2


Erythroferrone Regulates Bone
Remodeling in β-Thalassemia


Resident Physician

Naranie Shanmuganathan, MBBS, FRACP, FRCPA

Royal Adelaide Hospital and SA Pathology, Adelaide, Australia

Abstract

662


RNA Splicing Defects in
Cancer-Linked Genes Indicate Mutation or Focal Gene Deletion and Are Associated
with TKI Resistance in CML


Post-Doctoral Fellow

Tomoya Muto, MD PhD

Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

Abstract

727


Innate Immune Signaling Suppresses
Acute Leukemia By Modifying MYC Oncogenic Activity


Mary Rodes Gibson Memorial Award in Hemostasis and Thrombosis

The Mary Rodes Gibson Memorial Award in Hemostasis and Thrombosis was
established to recognize the trainee (undergraduate student, medical student,
graduate student, resident physician, or post-doctoral fellow) who is the first
author and presenter of the highest-scoring abstract submitted to the ASH
Annual Meeting in the field of hemostasis and thrombosis. This annual award
honoring excellence in hemostasis and thrombosis is made possible by the Mary
Rodes Gibson Hemostasis-Thrombosis Foundation to continue the legacy of Mary
Rodes Gibson, who suffered from severe, type 3 von Willebrand disease.

This award will be presented during the invited speaker session of the Special Symposium on the Basic Science of Hemostasis and Thrombosis on Monday, December 9, 2019 from 4:30 PM – 6:30 PM, OCCC, Tangerine 3 (WF3-4).

The 2019 recipient is:

Oluwatoyosi Muse, PhD

Beth Israel Deaconess Medical Center, Boston, MA

Abstract

632


The Unfolded Protein Response Causes Prothrombotic Transformation of
Pancreatic Cancer Linking Tumor Progression with Cancer-Associated Thrombosis



ASH-International Paroxysmal Interest Group Abstract Achievement Award for Paroxysmal Nocturnal Hemoglobinuria

2019 recipients are:

Hassan Awada, MD

Cleveland Clinic, Cleveland, Ohio

Abstract

2499


Molecular Characterization of Leukemia Evolving from Paroxysmal Nocturnal Hemoglobinuria

Tanabe Mikoto, MD

Kanazawa University, Kanazawa, Japan

Abstract

3736


A GPI-Anchored Protein, CD109, Protects Hematopoietic Progenitor Cells
from Erythroid Differentiation Induced By TGF-β.


Giuseppe Bigi Memorial Award

The ASH Giuseppe Bigi Memorial Award was established in 2015 to recognize an
Italian trainee (undergraduate student, medical student, graduate student,
resident physician, or post-doctoral fellow) based at an Italian institution
who has the highest-scoring abstract submitted in the field of hematopoiesis
and stem cells. This annual award is made possible by a generous grant from the Giuseppe Bigi Association, named for the late Giuseppe Bigi, MD, a well-known Italian scientist.

The 2019 recipient is:

Marilena Ciciarello, PhD

Azienda Ospedaliero-Universitaria S. Orsola- Malphighi, Bologna, Italy

Abstract

1212


Interferon-γ-Dependent Inflammatory Signature in Acute Myeloid
Leukemia Cells Is Able to Shape Stromal and Immune Bone Marrow Microenvironment



Giuseppe Bigi Abstract Achievement Award Recipient

The 2019 recipient is:

Annamaria April, PhD-IRCCS

San Raffaelle Scientific Institute, Milano, Italy

Abstract

967


Hematopoietic Stem Cell Function in β-Thalassemia Is Impaired and Is Rescued By Targeting the Bone Marrow Niche



ASH-British
Society of Haematology Abstract Achievement Award

2019 recipients are:

Sam Alimam, DHCS, MD

King’s College London, London, United Kingdom

Abstract

308


Molecular, Epigenetic and Gene Expression Profiling of Triple Negative
Essential Thrombocythaemia

Claire Burney, MBBS

University Hospitals Bristol, Bristol, United Kingdom

Abstract

701


Ibrutinib for Relapsed Mantle Cell Lymphoma after Standard First Line
Therapy and ASCT Is Efficacious but Does Not Overcome the Impact of POD24 – a
Retrospective Study from the LWP-EBMT

Konstantinos Tzelepis, PhD

University of Cambridge, Cambridge, United Kingdom

Abstract

403


Pharmacological Inhibition of the RNA m6a Writer METTL3 As a Novel
Therapeutic Strategy for Acute Myeloid Leukemia



ASH-Haematology Society of Australia and New Zealand Abstract Achievement Award

2019 recipient is:

Chong Chyn Chua, MBBS, FRACP, FRCPA

The Alfred Hospital and Monash University, Melbourne, Australia

Abstract

462


Anti-Leukemic Activity of Single Agent Venetoclax in Newly Diagnosed Acute
Myeloid Leukemia: A Sub-Set Analysis of the Caveat Study.



ASH-Japanese Society of Hematology Abstract Achievement Award

2019 recipients are:

Takeshi Fujino, MD

University of Tokyo, Tokyo, Japan

Abstract

821


Mutant ASXL1 Promotes Expansion of the Phenotypic Hematopoietic Stem Cell
Compartment

Haruko Shima, MD, PhD

Keio University School of Medicine, Tokyo, Japan

Abstract

25


Discontinuation of Tyrosine Kinase Inhibitor in Children with Chronic
Myeloid Leukemia (JPLSG STKI-14 study)

Koya Ono, MD

Tohoku University Graduate School of Medicine, Sendai, Japan

Abstract

3530


Molecular Characterization and Novel Therapeutic Strategy for X-Linked Siderblastic Anemia Associated with ALAS2 Missense Variants



ASH-Society Italiana di Ematologia Abstract Achievement Award

2019 recipients are:

Chiara Magnani, PhD

University of Milano-Bicocca/Fondazione MBBM, Milano, Italy

Abstract

200


Donor-Derived CD19 CAR Cytokine Induced Killer (CIK) Cells Engineered
with Sleeping Beauty Transposon for Relapsed B-Cell Acute Lymphoblastic
Leukemia (B-ALL)

Pier Edoardo Rovatti, MD

IRCCS San Raffaele Scientific Institute, Milano, Italy
Abstract

513


Exploiting an Anti-CD3/CD33 Bispecific Antibody to Redirect Donor T
Cells Against HLA Loss Leukemia Relapses


Minority Graduate Student Abstract Achievement Award

Each year, ASH offers merit-based Minority Graduate Student Abstract

Achievement Awards to select graduate students to honor their research accomplishments and to recruit and retain underrepresented minority graduate students in the field of hematology through exposure to the ASH Annual Meeting.

The 2019 Minority Graduate Student Abstract Achievement Award recipients are:

Adedamola Elujoba-Bridenstine, MS

University of Illinois at Chicago, Chicago, Illinois

Abstract

3707


The Neurotransmitter Receptor Gabbr1 Regulates Proliferation and Function of Hematopoietic Stem and Progenitor Cells

Marcus Florez, BS

Baylor College of Medicine, Houston, TX

Abstract

3726


IFNy Stimulation Induces Hematopoietic Stem Cell Homing and Niche Relocalization

Mohammed Gbadamosi, BS

University of Florida College of Pharmacy, Gainesville, FL

Abstract

908


Novel CD33 Antibodies Unravel Localization, Biology, and Therapeutic
Implications of CD33 Isoforms

Jamie Hamilton, BS

Emory University, Atlanta, GA

Abstract

1468


Elevated Levels of Interleukin-9 in Obese Microenvironments Promote
Leukemia Progression and Chemoresistance in B-Cell Acute Lymphoblastic Leukemia
Cells

Joseph Krambs, BS

Washington University School of Medicine, St. Louis, MO

Abstract

1209


Canonical Signaling By TGF Family Members in Mesenchymal Stromal
Cells Is Dispensable for Hematopoietic Niche Maintenance Under Basal and Stress
Conditions

Emaan Madany, BS

Cedars-Sinai Medical Center, Los Angeles, CA

Abstract

716


Increased Expression of Type 1 Interferon Stimulated Genes in Sickle
Cell Disease and a Potential Association with RBC Alloimmunization

###

A complete list of Abstract Achievement Award recipients will
be available at

https:/

/

www.

hematology.

org/

Awards/

Award-Recipients/

Abstract-Achievement/

The American Society of Hematology (ASH) (

http://www.

hematology.

org

) is the world’s largest professional society of hematologists dedicated to furthering the understanding, diagnosis, treatment, and prevention of disorders affecting the blood. For more than 60 years, the Society has led the development of hematology as a discipline by promoting research, patient care, education, training, and advocacy in hematology. ASH publishes

Blood

(

http://www.

bloodjournal.

org

), the most cited peer-reviewed publication in the field, and

Blood Advances

(

http://www.

bloodadvances.

org

), an online, peer-reviewed open-access
journal.


Contact:

Sara Khalaf, American Society of Hematology

[email protected]

“>


[email protected]


;
202-552-4925

This part of information is sourced from https://www.eurekalert.org/pub_releases/2019-11/asoh-aat110719.php

Sara Khalaf
202-552-4925
[email protected]
http://www.hematology.org 

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