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UrduArticle title: Circadian gene expression in mouse renal proximal tubule Authors: Molly A. Bingham, Kim Neijman, Chin-Rang Yang, Angel Aponte, Angela Mak, Hiroaki Kikuchi, Hyun Jun Jung, Brian G. Poll, Viswanathan Raghuram, Euijung Park, Chung-Lin Chou, Lihe Chen, Jens Leipziger,…
Month: April 2023
Tired of being alone: How social isolation impacts on our energy
In a study conducted in the lab as well as during the COVID-19 lockdowns, participants reported higher levels of tiredness after eight hours of social isolation. The results suggest that low energy may be a basic human response to a lack of social contact. The study conducted at the University of Vienna and published in Psychological Science also showed that this response was affected by social personality traits of the participants.
Researchers Visualize Lung Alveolar Structure in 3D
Article title: Analysis of the alveolar shape in 3D Authors: Alex M. Reimelt, Dragoș M. Vasilescu, Richard Beare, Jonas Labode, Lars Knudsen, Roman Grothausmann From the authors: “This study provides a new method for the quantification and visualization of alveolar…
Researchers Explore Sex Differences in Cardiovascular and Congenital Heart Diseases in People with Down Syndrome
Article title: Sex differences in cardiovascular disease and dysregulation in Down syndrome Authors: Melissa L. Bates, Anastasiia Vasileva, Laura D.M. Flores, Yana Pryakhina, Michelle Buckman, Michael H. Tomasson, Lara R. DeRuisseau From the authors: “Based on the results of our…
Diabetes Drug Improves Kidney Function and Inflammation
Article title: Reno-protective effects of empagliflozin are linked to activation of the tubuloglomerular feedback mechanism and blunting of the complement system Authors: Xin Chen, Denis Delić, Yaochen Cao, Linghong Shen, Qin Shao, Zheyu Zhang, Hongwei Wu, Ahmed A. Hasan, Christoph…
Succinate Protects against Obesity, Metabolic Disease through Brown Fat Protein Expression
Article title: Exogenous succinate impacts mouse brown adipose tissue mitochondrial proteome and potentiates body mass reduction induced by liraglutide Authors: Rodrigo S. Gaspar, Jeany Delafiori, Giuliana Zuccoli, Victor Corasolla Carregari, Thais P. Prado, Joseane Morari, Davi Sidarta-Oliveira, Carina S. Solon,…
Does getting a cold often increase your risk for dementia? New study finds link
Getting sick often may impact how quickly the brain ages and increase the risk of dementia or other forms of cognitive decline.
Por que tenho dores no ombro?
Se sentir dores no ombro após movimentar o braço, talvez você tenha um problema nele. A dor no ombro pode ser um sinal de artrite, tendinite, ruptura do manguito rotador ou instabilidade no ombro.
¿Por qué me duele el hombro?
Si siente la necesidad de frotarse el hombro después de haber usado el brazo, podría tener un problema en el hombro. El dolor de hombro puede ser un signo de artritis, tendinitis, desgarro del manguito rotador o inestabilidad del hombro.
لماذا يؤلمني كتفي؟
إذا وجدت أنك تدلك كتفك بعد استخدام ذراعك، فربما يكون لديك مشكلة في الذراع. فألم الذراع قد يكون علامة على الإصابة بالتهاب المفاصل، أو التهاب الأوتار، أو تمزق الكُفة المدوّرة، أو عدم استقرار مفصل الكتف.
NASA Awards Astrophysics Postdoctoral Fellowships for 2023
The NHFP fosters excellence and leadership in NASA astrophysics by supporting some of the most promising and innovative young astrophysicists.
Hidden ice melt in Himalaya: Study
A new study reveals that the mass loss of lake-terminating glaciers in the greater Himalaya has been significantly underestimated, due to the inability of satellites to see glacier changes occurring underwater, with critical implications for the region’s future projections of glacier disappearance and water resources.
Illegal trade and poor regulation threaten pangolins in China
Pangolins, unique scale-covered mammals, are drastically declining in numbers across Asia and Africa, largely due to illegal trade. Part of the trade, both legal and illegal, supports the traditional Chinese medicine market, which has attracted conservation attention.
How do we know if our brain is capable of repairing itself?
Is our brain able to regenerate? And can we harness this regenerative potential during aging or in neurodegenerative conditions? These questions sparked intense controversy within the field of neuroscience for many years.
Cells refine palm fat into olive oil
Fat molecules serve as energy storage for fat cells. They consist of three fatty acids attached to a backbone of glycerol. They are therefore also called triglycerides. It has long been suspected that molecules do not remain unchanged during their storage period.
Smart watches could predict higher risk of heart failure
The peer-reviewed study, published in The European Heart Journal – Digital Health, looked at data from 83,000 people who had undergone a 15-second electrocardiogram (ECG) comparable to the kind carried out using smart watches and phone devices.
Cold is beneficial for healthy aging
Cold activates a cellular cleansing mechanism that breaks down harmful protein aggregations responsible for various diseases associated with aging.
Use of racially concordant educational video did not affect acceptance of heart implant devices among Black patients
Multiple studies have demonstrated that Black patients are significantly less likely than white patients to undergo invasive cardiovascular procedures. Prior research also has demonstrated substantial racial disparities in the use of implantable cardioverter-defibrillators (ICDs) that can be lifesaving for those at high risk for sudden cardiac death.
English language pushes everyone – even AI chatbots – to improve by adding
Language related to the concept of ‘improvement’ is more closely aligned with addition, rather than subtraction. This can lead us to make decisions which can overcomplicate things we are trying to make better.
Uneven Indian Ocean Warming unlocked
A study published in Nature Communications by an international team of climate scientists uncovers the physical mechanisms that can cause uneven future warming in the Indian Ocean and corresponding shifts in monsoon precipitation.
Late HIV diagnosis still an issue in Aotearoa
Forty per cent of people diagnosed with HIV in Aotearoa between 2011 and 2020 were diagnosed late, a University of Otago study shows.
AAOS Announces Call for Proposals for Inspiring Diversity, Equity and Access Projects Across Orthopaedics
The American Academy of Orthopaedic Surgeons (AAOS) today announced a call for proposals for the AAOS IDEA Grant Program, a multi-year initiative to inspire diversity, equity and access across the field of orthopaedics. Now in its second year, the program will award $300,000 in 2024 to help address decades of inertia surrounding persistent disparities across orthopaedics and, in turn, better serve patients nationwide.
During Oral Cancer Awareness Month, AANA Emphasizes Access to Safe Dental Anesthesia Care
April is Oral Cancer Awareness Month, and the American Association of Nurse Anesthesiology (AANA) reminds the public that the best prevention of oral health is early detection. Also, of critical importance is ensuring patients have access to safe anesthesia care when treatments including surgery are used for oral cancer.
Awareness vital to improving Parkinson’s patients’ quality of life, UTSW neurologist says
About 1 million people in the United States have Parkinson’s disease, a progressive neurological disorder that ranks second to Alzheimer’s among the most common neurodegenerative diseases. While many tend to associate Parkinson’s with hand tremors, it can cause a broad range of symptoms, affecting both motor and nonmotor functions.
Study: ChatGPT Has Potential to Help Cirrhosis, Liver Cancer Patients
A new study by Cedars-Sinai investigators describes how ChatGPT, an artificial intelligence (AI) chatbot, may help improve health outcomes for patients with cirrhosis and liver cancer by providing easy-to-understand information about basic knowledge, lifestyle and treatments for these conditions.
Patient Advocates and Health Care Professionals Call on CMS to Ensure Access to DIEP Flap Breast Reconstruction
Advocates for individuals in need of breast reconstruction surgery delivered a letter and petition to the Centers for Medicare and Medicaid Services (CMS) today, urging them to reinstate a procedure code that is essential for access to deep inferior epigastric perforator (DIEP) flap breast reconstruction surgery. The numbers of those signing the letter and petition keep growing.
Smells influence metabolism and ageing in mice – research
Exposure to female odours and pheromones causes weight loss and extend the life spans of mice, which may have implications for humans, University of Otago researchers have found.
Wastewater more potent breeding ground for antibiotic resistance than previously known
Wastewater is a more potent environment for antibiotic resistance to evolve than previously known.
E-health reduces patient pain, opioids in clinical study
An online “e-health” program helped more people with chronic pain reduce their opioid medications and pain intensity than a control group that had only regular treatment in a recent clinical study.
Tratamiento inadecuado de primera línea para el estado epiléptico: el problema y las soluciones
A pesar de las directrices, el tratamiento de primera línea para el estado epiléptico a menudo es inadecuado. Los estudios sugieren que hasta dos tercios de los pacientes reciben dosis subclínicas de benzodiazepinas, ya sea antes de llegar a un hospital o durante el tratamiento hospitalario de emergencia. ¿Hay soluciones?
Irvine Health Foundation’s $14 million grant to UC Irvine will establish 7 endowed chairs
A $14 million grant from the Irvine Health Foundation to the University of California, Irvine will establish seven endowed chairs in the Program in Public Health to recruit and retain the field’s top academic leaders and experts, who will strive for health equity among all Orange County residents.
Older adults perceive artificial intelligence as more human-like than younger adults do
Artificial intelligence (AI) is increasingly present in all of our lives, from newer offerings like ChatGPT to more established voice systems such as automated phone services, self-checkouts, Apple’s Siri and Amazon’s Alexa.
Rising Temperatures Alter ‘Missing Link’ of Microbial Processes, Putting Northern Peatlands at Risk
Georgia Tech researchers show that rising temperatures in northern regions may damage peatlands: critical ecosystems for storing carbon from the atmosphere — and could decouple vital processes in microbial support systems.
Anticancer drugs with fewer side-effects: scientists decode the crystal structure of a key cell cycle protein
Anticancer drugs are pivotal to cancer treatment, but their toxicity may not always be limited to cancer cells, resulting in harmful side-effects.
Jet lag’s harmful health impacts found to be caused by biological clock misalignment
New research at the University of Massachusetts Amherst zeroes in on the root cause of adverse health effects from disruption of the body’s circadian rhythms, which typically occurs from jet lag and rotating work shifts.
Multilab Separations Consortium puts biofuel on the path to decarbonization
BETO Bioprocessing Separations Consortium spotlights projects from three-year work period.
New Research Shows That Bacteria Get “Hangry,” Too
The findings, published in Nature Microbiology, are particularly important in understanding how and why bacterial communities defer duties to certain cells – and could lead to new ways to tackle antibiotic tolerance further down the line.
Researchers Show Lorlatinib is Safe and Effective for Patients with ALK-Driven Relapsed/Refractory High-Risk Neuroblastoma
In a significant step for the treatment of neuroblastoma, an international group of researchers led by Children’s Hospital of Philadelphia (CHOP), Winship Cancer Institute of Emory University and the New Approaches to Neuroblastoma Therapy (NANT) Consortium has shown that the targeted therapy lorlatinib is safe and effective in treating high-risk neuroblastoma.
More U.S. Prostate Cancer Patients Choosing Active Surveillance
The number of prostate cancer patients in the U.S. choosing active surveillance over surgery or radiation has rapidly increased since 2010, rising from 16% to 60% for low-risk patients and from 8% to 22% for patients with favorable-intermediate-risk cancers, according to a study published today in JAMA Internal Medicine.
Research finds global emissions of several banned ozone-destroying chemicals are increasing
New analysis has found increasing emissions of several ozone-depleting chemicals despite their production being banned for most uses under the Montreal Protocol – and a loophole in the rules is likely responsible.
Higher lithium levels in drinking water may raise autism risk
Pregnant women whose household tap water had higher levels of lithium had a moderately higher risk of their offspring being diagnosed with autism spectrum disorder, researchers reported in JAMA Pediatrics.
AstraGin®, Developed by NuLiv Science, Demonstrates Improvements in Gut Health in Human Clinical Trial
A groundbreaking human clinical trial published in the Journal of Biochemistry and Biotechnology reveals AstraGin®’s significant impact on various factors related to gut health in patients with Ulcerative Colitis (UC).
A Former SEAL Medic Hopes His Research at Rutgers Will Protect His Successors in Combat
Shane Kronstedt’s experience in battle inspired his medical school research on genital and urologic injuries.
Study Finds Certain Substances in Urine, Blood Can Predict Kidney Disease Progression
In a new study looking at the long-term effects of hospitalized patients who have acute kidney injury (AKI), a sudden but temporary loss of kidney function, Johns Hopkins Medicine researchers found that higher levels of certain biomarkers in urine and blood can predict a patient’s risk of developing chronic kidney disease (CKD).
Mount Sinai Awarded Prestigious $1.3 Million Grant to Expand Research Training Program in Skin Biology
The Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai will expand its research training program in skin biology with support from a five-year, $1.3 million T32 grant from the National Institutes of Health (NIH) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).
Initiative Improves Alarm Management, Reduces Alarm Fatigue
A Florida hospital’s surgical ICU used the CEASE bundle to improve nurses’ alarm management practices and reduce nurses’ self-reported alarm fatigue, according to a study in Critical Care Nurse.
Warming Strongly Increases Nutrient Availability in a Nutrient-Limited Bog
Whole-ecosystem warming at SPRUCE exponentially increased available nutrients for plants, but observed responses were not captured by the ELM-SPRUCE model.
Extremely rare gene variants point to a potential cause of age-related macular degeneration
A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.
April 2023 Issue of Neurosurgical Focus: Video: “Intraventricular Endoscopic Surgery”
Announcement of contents of the April 2023 issue of Neurosurgical Focus: Video
April 2023 Issue of Neurosurgical Focus: “Adult Hydrocephalus: Advancements in Diagnosis, Treatment, and Patient Outcomes”
Announcement of contents of the April 2023 issue of Neurosurgical Focus