Coronavirus Race for Survival in the Epithelium: the Fastest Autowave Wins the Competition of Viral Strains

Scientists from the Nikol’skii Mathematical Institute of RUDN University built a mathematical model that describes the self-sustaining propagation of virus concentration waves – autowaves – in a tissue or cell culture, taking into account their competition for resources, that is the infected cells. The authors applied the constructed model to study variants of the new coronavirus, Delta and Omicron. It turned out that the autowave with the higher speed of spatial propagation wins, while the slow autowave dies. The studied processes relate to the competition and evolution of viral strains in the upper respiratory tract in vivo. In addition, the proposed approaches can be used when creating new methods for studying viruses in vitro.

Powered by artificial intelligence, Argonne technology eyes bird activity at solar facilities

The World Health Organization says monkeypox is a global health emergency. Scientists use ultrabright X-ray beams and diffraction imagery to understand how poxviruses behave. This can accelerate development of critical vaccines and treatments for monkeypox and other poxviruses.

Dual-targeting CAR NK cells can prevent cell dysfunction and tumor escape

Researchers at The University of Texas MD Anderson Cancer Center have developed a new approach to engineering natural killer (NK) cells with a second chimeric antigen receptor (CAR) to act as a logic gate, requiring two signals to eliminate a target cell. In preclinical studies, these next-generation CAR NK cells improved tumor specificity and enhanced anti-tumor activity by overcoming a process that contributes to NK cell dysfunction and tumor relapse.

Dietary supplementation may improve antibiotic-induced GVHD following stem cell transplants

Researchers at The University of Texas MD Anderson Cancer Center have identified a specific gut bacterium involved in the progression of graft-versus-host disease (GVHD) after antibiotic treatment of allogeneic hematopoietic stem cell transplantation (allo-HSCT) and discovered that nutritional supplementation can prevent antibiotic-induced GVHD in preclinical models, according to a study published today in Cell.

Webb, Hubble Capture Detailed Views of DART Impact

Two of NASA’s great observatories had a front row seat to a first of its kind NASA test for defending Earth against potential asteroid or comet hazards.
NASA’s James Webb Space Telescope and Hubble Space Telescope teamed up to collect data before and after NASA’s Double Asteroid Redirection Test (DART) intentionally slammed into Dimorphos, the asteroid moonlet in the double-asteroid system of Didymos, at nearly 15,000 miles per hour.
Not only will ground-based telescope observations help determine how successful the test was in altering the asteroid’s orbit, but the combined capabilities of Webb and Hubble together —on the same target, at the same time— will allow scientists to analyze a wide array of data relating to the makeup and history of our solar system.

Low long-term risk of breast cancer recurrence after nipple-sparing mastectomy

Nipple-sparing mastectomy (NSM) – an increasingly popular option for women undergoing treatment for breast cancer – not only achieves good cosmetic outcomes, but also low long-term risk of recurrent breast cancer, reports a study in the October issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Combined oral contraceptives don’t increase the risk of macromastia in young women

Combined oral contraceptives (COCs) containing both estrogen and progestin do not contribute to the development of enlarged breasts (macromastia) – nor do they increase the risk of breast regrowth in adolescents and young women following breast-reduction surgery, reports a study in the October issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Breast Cancer Expert: “Awareness and Early Detection Save Lives”

One in eight women will be diagnosed with breast cancer in her lifetime.    For those with BRCA1 and BRCA2 gene mutations, the chances are even higher. The National Breast Cancer Foundation estimates that 55 to 65% of women with the BRCA1 mutation, and 45%…

NAU research collaborative receives $21M grant to continue pioneering work into health equity in the Southwest

A groundbreaking research collaborative at Northern Arizona University received another $21 million grant to continue its work to promote health equity and study health disparities among diverse populations of the American Southwest.

Active Matter, Curved Spaces: Mini Robots Learn to ‘Swim’ on Stretchy Surfaces

Physicists are using small wheeled robots to better understand indirect mechanical interactions, how they play a role in active matter, and how we can control them. Their findings, “Robotic swimming in curved space via geometric phase” are recently published in the The Proceedings of the National Academy of Sciences (PNAS).

MD Anderson Research Highlights for September 28, 2022

The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts. Current advances include an investigation into the efficacy of dexamethasone for dyspnea relief, a combination therapy for hairy cell leukemia, an analysis of RAS mutations and their prognostic value in acute myeloid leukemia (AML), a possible new combination therapy for basal-like breast cancer, and swallowing exercises to improve the quality of life for patients with head and neck cancer undergoing radiotherapy.

Rate of food insecurity skyrockets for Americans with cardiovascular disease, study finds

The number of Americans with cardiovascular disease who are food insecure – having limited or uncertain access to adequate food – has more than doubled over the last 20 years, a national study finds. Adults with cardiovascular disease were more than two times likely to be food insecure than those without the cardiovascular disease.

Hubble Detects Protective Shield Defending a Pair of Dwarf Galaxies

Researchers have used Hubble and FUSE observations of ultraviolet light from quasars to detect and map the Magellanic Corona, a diffuse halo of hot, supercharged gas surrounding the Small and Large Magellanic Clouds. Shown in purple, the corona stretches more than 100,000 light-years from the main mass of stars, gas, and dust that make up the Magellanic Clouds, intermingling with the hotter and more extensive Milky Way Corona, shown in blue. The corona is thought to act as a buffer protecting the dwarf galaxies’ vital star-forming gas from the gravitational pull of the much larger Milky Way.

AI-guided screening uses ECG data to detect a hidden risk factor for stroke

An AI-guided targeted screening strategy is effective in detecting new cases of atrial fibrillation that would not have come to attention in routine clinical care.
This strategy could reduce the number of undiagnosed cases of atrial fibrillation, and prevent stroke and death in millions of patients across the globe.

People who feel less pain are also less willing to help others

A reduced ability to feel pain in one’s own body leads to a reduced willingness to help others who feel pain. This result of a study published in Psychological Science by cognitive psychologists at the University of Vienna led by Claus Lamm and Helena Hartmann points beyond the individual effects of pain medication to its social costs.

Machine learning creates opportunity for new personalized therapies

Researchers at the University of Michigan Rogel Cancer Center have developed a computational platform that can predict new and specific metabolic targets in ovarian cancer, suggesting opportunities to develop personalized therapies for patients that are informed by the genetic makeup of their tumors. The study appeared in Nature Metabolism.

Potential First Traces of the Universe’s Earliest Stars

Astronomers may have discovered the ancient chemical remains of the first stars to light up the Universe. Using an innovative analysis of a distant quasar observed by the 8.1-meter Gemini North telescope on Hawai‘i, operated by NSF’s NOIRLab, the scientists found an unusual ratio of elements that, they argue, could only come from the debris produced by the all-consuming explosion of a 300-solar-mass first-generation star.

Descubren evidencias de las primeras estrellas del Universo

Un equipo internacional de astrónomos halló evidencia de antiguos vestigios químicos de las primeras estrellas que iluminaron el Universo. Usando un análisis innovador de un cuásar distante observado por el telescopio Gemini Norte de 8,1 metros en Hawai’i, y que opera NOIRLab de la NSF, los científicos encontraron una proporción inusual de elementos que, según ellos, sólo podrían provenir de los desechos producidos en la explosión de una estrella de primera generación de 300 masas solares.

NRAO’s Marian Pospieszalski Receives EuMA Pioneer Award

The European Microwave Association (EuMA) has announced Marian Pospieszalski— a senior research engineer at the National Science Foundation’s National Radio Astronomy Observatory (NRAO)— as the recipient of its 2022 Pioneer Award. The EuMA Pioneer Award recognizes individuals responsible for noteworthy advances in the field of microwaves that have had a lasting and significant impact on the microwave community.

$50 Million Gift to Accelerate Colton Center for Autoimmunity at Penn Medicine

A $50 million gift from Stewart and Judy Colton will accelerate the existing Colton Center for Autoimmunity at the University of Pennsylvania’s Perelman School of Medicine into an internationally leading center of autoimmune research and treatment with a dedicated space, powerful recruitment capabilities, scientific resources, and more. This gift builds on a $10 million gift from the Coltons, which established the Colton Center for Autoimmunity at Penn in the fall of 2021.