Newly approved drug effective against lung cancer caused by genetic mutation

The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial led by Washington University School of Medicine in St. Louis. The drug is designed to shut down the effects of the mutation, which is found in about 13% of patients with lung adenocarcinoma, a common type of non-small-cell lung cancer.

Newly approved targeted therapy sotorasib prolongs survival in KRAS G12C-mutated lung cancer

Results from the Phase II cohort of the CodeBreaK 100 study showed that treatment with the KRAS G12C inhibitor sotorasib achieved 12.5 months median overall survival in previously treated patients with KRAS G12C-mutated non-small cell lung cancer, according to researchers from The University of Texas MD Anderson Cancer Center.

UHN announces first-in-Canada Social Medicine Modular Housing in Parkdale, in partnership with the City and United Way Greater Toronto

University Health Network (UHN) and the Gattuso Centre for Social Medicine, in partnership with the City of Toronto and United Way Greater Toronto (UWGT), are creating what is believed to be the first of its kind in Canada, Social Medicine Supportive Housing site in Parkdale, Toronto.

Mount Sinai identifies the causes of racial disparity in prostate cancer in a multi-institutional study

MEDIA ADVISORY Senior Author:  Ash Tewari, MBBS, MCh, Professor and System Chairman of the Milton and Carroll Petrie Department of Urology at the Icahn School of Medicine at Mount Sinai and Director of the Center of Excellence for Prostate Cancer…

Understanding the skin’s defense system

It can be easy to forget that the human skin is an organ. It’s also the largest one and it’s exposed, charged with keeping our inner biology safe from the perils of the outside world.

But Michigan State University’s Sangbum Park is someone who never takes skin or its biological functions for granted. He’s studying skin at the cellular level to better understand it and help us support it when it’s fighting injury, infection or disease.

Bacteria are connected to how babies experience fear

New research from MSU shows that an infant’s gut microbiome could contain clues to help monitor and support healthy neurological development

Why do some babies react to perceived danger more than others? According to new research from Michigan State University and the University of North Carolina, Chapel Hill, part of the answer may be found in a surprising place: an infant’s digestive system.

Most Californians unaware of law to prevent gun violence but would support using it

A new study shows that two-thirds of Californians don’t know about a law designed to prevent a person at risk of hurting themselves or others from possessing or purchasing firearms or ammunition. More than 80% of survey participants were supportive once they read about this law.

ADHD Medications Associated with Reduced Risk of Suicidality in Children with Significant Behavioral Symptoms

ADHD medications may lower suicide risk in children with hyperactivity, oppositional defiance and other behavioral disorders, according to new research from the Lifespan Brain Institute (LiBI) of Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania. The findings, published today in JAMA Network Open, address a significant knowledge gap in childhood suicide risk and could inform suicide prevention strategies at a time when suicide among children is on the rise.

Prudence Carter Elected 113th ASA President; Mignon Moore Voted Vice President

WASHINGTON, DC—Prudence L. Carter, E.H. and Mary E. Pardee Professor and Dean of the Graduate School of Education, University of California-Berkeley, has been elected the 113th President of the American Sociological Association (ASA). Mignon R. Moore, Professor of Sociology, Barnard College and Columbia University, has been elected ASA Vice President. Carter and Moore will serve as President- and Vice President-elect for one year before succeeding Cecilia Menjívar, University of California-Los Angeles, and Nina Bandelj, University of California-Irvine, respectively, in August 2022.

One in Three Americans Still Practice Unsafe Storage of Popular Laundry Products

Recent data from American Cleaning Institute shows a need for continued safety education and awareness when it comes to using and storing liquid laundry packets and other household cleaners. As National Safety Month gets underway, ACI is reminding everyone not to forget the common-sense steps we need to take to keep our children safe in the home.

Remote patient monitoring may reduce need to hospitalize cancer patients

ROCHESTER, Minn. — A study by researchers at Mayo Clinic Cancer Center has found that cancer patients diagnosed with COVID-19 who received care at home via remote patient monitoring were significantly less likely to require hospitalization for their illness, compared to cancer patients with COVID-19 who did not participate in the program. Results of the study were presented Friday, June 4, at the American Society of Clinical Oncology Annual Meeting and published in the Journal of Clinical Oncology.

New findings offer improved therapy of early-stage, BRCA mutation-associated breast cancer

Results were released this week on a new treatment with the potential to improve the outcomes for patients with hereditary BRCA mutations and high-risk, early-stage breast cancer. These results represent the first time a drug that blocks cancer cells from repairing their DNA (called a PARP inhibitor) has been shown to significantly reduce the risk of breast cancer returning in high-risk patients following completion of standard chemotherapy, surgery and radiation therapy.

Giving Brown Fat A Boost to Fight Type 2 Diabetes

DALLAS – June 4, 2021 – Increasing a protein concentrated in brown fat appears to lower blood sugar, promote insulin sensitivity, and protect against fatty liver disease by remodeling white fat to a healthier state, a new study led by UT Southwestern scientists suggests. The finding, published online in Nature Communications, could eventually lead to new solutions for patients with diabetes and related conditions.

Disparities in COVID-19 Rates among Adults with Kidney Failure in New York City

• Among adults with kidney failure undergoing hemodialysis in New York City, Black and Hispanic patients were more likely to develop symptomatic COVID-19 than White patients.
• Neighborhood-level social vulnerability factors were associated with COVID-19 incidence among White patients, but these factors did not explain racial/ethnic disparities.

June 4 Research Highlights from ACSM Annual Meeting

ACSM’s comprehensive sports medicine and exercise science conference takes place virtually from June 1 to 5 with programming covering the science, practice, public health and policy aspects of sports medicine, exercise science and physical activity. View program highlights.

New research may offer hope for Alzheimer’s patients

University of Kentucky Neuroscience Professor Greg Gerhardt’s new research program will provide answers to long-standing questions about the role of neurotransmitters GABA and glutamate in the progression of Alzheimer’s disease. A culmination of his nearly 40 years of brain research, Gerhardt’s study could help to develop new treatments for the disease.

Predicting the ocean: Improved forecast and insights for the Mediterranean and Black Seas

Marine forecasters face the challenge of predicting a very complex and constantly changing marine environment by applying ocean science, knowledge and technological skills to produce predictions of the state of the ocean . Operational forecasts are delivered daily in near…

Adapting laboratory techniques for remote instruction

The COVID-19 pandemic forced instructors to adapt their courses for online learning. Laboratory courses were particularly difficult due to lack of access to specialized equipment for remote learners. To overcome this challenge, researchers from the University of Illinois Urbana-Champaign designed…

Researcher gets $2.7 million grant to study seasonal and universal vaccination in aged populations

ATLANTA–Dr. Sang-Moo Kang, professor in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.7 million federal grant to study seasonal and universal vaccination in elderly populations with pre-existing immunity to influenza viruses. The grant from…

Structural uniqueness of the green- and red-light sensing photosensor in cyanobacteria

Overview: Certain cyanobacteria can change the absorbing light colors for photosynthesis using a green- and red-light sensing photosensor protein. A Japanese research group elucidated the molecular structure of RcaE, a representative member of the photosensors. They revealed the unique conformation…

Technique inspired by lace making could someday weave structures in space

Lauren Dreier was paging through a 19th century book by the German architect Gottfried Semper when she spotted some intriguing patterns inspired by lace. A professional artist and designer who often incorporates technology into her work, Dreier, who is also…

The 8th International Horticulture Research Conference Announcement

To showcase the latest achievements and research progress in the field of horticulture, and promote communication and cooperation among world experts, the 8th International Horticulture Research Conference will be held from July 20 to 22, 2021 in Nanjing, China, and…