Innovative research refines the treatment of patients with advanced cancers and the use of immunotherapy
Month: June 2021
Newly approved drug effective against lung cancer caused by genetic mutation
The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial led by Washington University School of Medicine in St. Louis. The drug is designed to shut down the effects of the mutation, which is found in about 13% of patients with lung adenocarcinoma, a common type of non-small-cell lung cancer.
Soft tissue measurements critical to hominid reconstruction
Accurate soft tissue measurements are critical when making reconstructions of human ancestors, a new study from the University of Adelaide and Arizona State University has found.
Newly approved targeted therapy sotorasib prolongs survival in KRAS G12C-mutated lung cancer
Results from the Phase II cohort of the CodeBreaK 100 study showed that treatment with the KRAS G12C inhibitor sotorasib achieved 12.5 months median overall survival in previously treated patients with KRAS G12C-mutated non-small cell lung cancer, according to researchers from The University of Texas MD Anderson Cancer Center.
COVID-19 pandemic has had significant impact on the mental health of adolescents
A study of over 59,000 Icelandic adolescents by a team of Icelandic and North American behavioral and social scientists found that COVID-19 has had a significant, detrimental impact on adolescent mental health, especially in girls.
Geologist identifies new form of quasicrystal
A UMass Lowell geologist is among the researchers who have discovered a new type of manmade quasicrystal created by the first test blast of an atomic bomb.
New study into green tea’s potential to help tackle COVID-19
As India continues to be ravaged by the pandemic, a Swansea University academic is investigating how green tea could give rise to a drug capable of tackling Covid-19.
NASA Awards The University of Texas at El Paso $2 Million Grant
The University of Texas at El Paso has earned a $2 million grant from NASA to develop technologies to mine ice on the moon for future deep space exploration.
Collaboration controls killers
St. Jude immunologists are researching how effector and killer T cells can be controlled to destroy cancer cells that resist treatment.
UHN announces first-in-Canada Social Medicine Modular Housing in Parkdale, in partnership with the City and United Way Greater Toronto
University Health Network (UHN) and the Gattuso Centre for Social Medicine, in partnership with the City of Toronto and United Way Greater Toronto (UWGT), are creating what is believed to be the first of its kind in Canada, Social Medicine Supportive Housing site in Parkdale, Toronto.
Dollars to donuts: What will it take to get more of the U.S. vaccinated against COVID-19?
Prizes, lotteries, discounts and freebies for COVID-19 vaccination may help overcome vaccine hesitancy and reward the vaccinated too, but it’s important to learn from this moment to inform other preventive health care, an expert says.
Measuring Teaching Practices at Scale: A Novel Application of Text-as-Data Methods
Abstract Valid and reliable measurements of teaching quality facilitate school-level decision-making and policies pertaining to teachers. Using nearly 1,000 word-to-word transcriptions of fourth- and fifth-grade English language arts classes, we apply novel text-as-data methods to develop automated measures of teaching…
Mount Sinai identifies the causes of racial disparity in prostate cancer in a multi-institutional study
MEDIA ADVISORY Senior Author: Ash Tewari, MBBS, MCh, Professor and System Chairman of the Milton and Carroll Petrie Department of Urology at the Icahn School of Medicine at Mount Sinai and Director of the Center of Excellence for Prostate Cancer…
Understanding the skin’s defense system
It can be easy to forget that the human skin is an organ. It’s also the largest one and it’s exposed, charged with keeping our inner biology safe from the perils of the outside world.
But Michigan State University’s Sangbum Park is someone who never takes skin or its biological functions for granted. He’s studying skin at the cellular level to better understand it and help us support it when it’s fighting injury, infection or disease.
Bacteria are connected to how babies experience fear
New research from MSU shows that an infant’s gut microbiome could contain clues to help monitor and support healthy neurological development
Why do some babies react to perceived danger more than others? According to new research from Michigan State University and the University of North Carolina, Chapel Hill, part of the answer may be found in a surprising place: an infant’s digestive system.
Most Californians unaware of law to prevent gun violence but would support using it
A new study shows that two-thirds of Californians don’t know about a law designed to prevent a person at risk of hurting themselves or others from possessing or purchasing firearms or ammunition. More than 80% of survey participants were supportive once they read about this law.
ADHD Medications Associated with Reduced Risk of Suicidality in Children with Significant Behavioral Symptoms
ADHD medications may lower suicide risk in children with hyperactivity, oppositional defiance and other behavioral disorders, according to new research from the Lifespan Brain Institute (LiBI) of Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania. The findings, published today in JAMA Network Open, address a significant knowledge gap in childhood suicide risk and could inform suicide prevention strategies at a time when suicide among children is on the rise.
Statewide quality improvement project reduced excessive radiation treatments for bone metastases by 80%
An effort by the Michigan Radiation Oncology Quality Consortium reduced unnecessary radiation therapy procedures, and saved the time and resources of patients and families.
Prudence Carter Elected 113th ASA President; Mignon Moore Voted Vice President
WASHINGTON, DC—Prudence L. Carter, E.H. and Mary E. Pardee Professor and Dean of the Graduate School of Education, University of California-Berkeley, has been elected the 113th President of the American Sociological Association (ASA). Mignon R. Moore, Professor of Sociology, Barnard College and Columbia University, has been elected ASA Vice President. Carter and Moore will serve as President- and Vice President-elect for one year before succeeding Cecilia Menjívar, University of California-Los Angeles, and Nina Bandelj, University of California-Irvine, respectively, in August 2022.
One in Three Americans Still Practice Unsafe Storage of Popular Laundry Products
Recent data from American Cleaning Institute shows a need for continued safety education and awareness when it comes to using and storing liquid laundry packets and other household cleaners. As National Safety Month gets underway, ACI is reminding everyone not to forget the common-sense steps we need to take to keep our children safe in the home.
Remote patient monitoring may reduce need to hospitalize cancer patients
ROCHESTER, Minn. — A study by researchers at Mayo Clinic Cancer Center has found that cancer patients diagnosed with COVID-19 who received care at home via remote patient monitoring were significantly less likely to require hospitalization for their illness, compared to cancer patients with COVID-19 who did not participate in the program. Results of the study were presented Friday, June 4, at the American Society of Clinical Oncology Annual Meeting and published in the Journal of Clinical Oncology.
New findings offer improved therapy of early-stage, BRCA mutation-associated breast cancer
Results were released this week on a new treatment with the potential to improve the outcomes for patients with hereditary BRCA mutations and high-risk, early-stage breast cancer. These results represent the first time a drug that blocks cancer cells from repairing their DNA (called a PARP inhibitor) has been shown to significantly reduce the risk of breast cancer returning in high-risk patients following completion of standard chemotherapy, surgery and radiation therapy.
Saint Louis University Successfully Completes Academic Year Amid Pandemic
Saint Louis University has successfully wrapped up its 2020-2021 academic year — one that brought unprecedented challenges due to a global pandemic — without having to suspend its commitment to mostly in-person classes, entirely in-person labs and on-campus living.
Giving Brown Fat A Boost to Fight Type 2 Diabetes
DALLAS – June 4, 2021 – Increasing a protein concentrated in brown fat appears to lower blood sugar, promote insulin sensitivity, and protect against fatty liver disease by remodeling white fat to a healthier state, a new study led by UT Southwestern scientists suggests. The finding, published online in Nature Communications, could eventually lead to new solutions for patients with diabetes and related conditions.
UTHealth professor awarded CPRIT grant for research training program
Zhongming Zhao, PhD, MS, with The University of Texas Health Science Center at Houston (UTHealth), has been awarded nearly $4 million from the Cancer Prevention and Research Institute of Texas (CPRIT) to provide research training to help with cancer prevention.
Disparities in COVID-19 Rates among Adults with Kidney Failure in New York City
• Among adults with kidney failure undergoing hemodialysis in New York City, Black and Hispanic patients were more likely to develop symptomatic COVID-19 than White patients.
• Neighborhood-level social vulnerability factors were associated with COVID-19 incidence among White patients, but these factors did not explain racial/ethnic disparities.
June 4 Research Highlights from ACSM Annual Meeting
ACSM’s comprehensive sports medicine and exercise science conference takes place virtually from June 1 to 5 with programming covering the science, practice, public health and policy aspects of sports medicine, exercise science and physical activity. View program highlights.
Preventing suicide among a ‘hidden population’ in public housing
New research suggests that African American families living in public housing are a “hidden population” when it comes to national suicide prevention efforts.
New research may offer hope for Alzheimer’s patients
University of Kentucky Neuroscience Professor Greg Gerhardt’s new research program will provide answers to long-standing questions about the role of neurotransmitters GABA and glutamate in the progression of Alzheimer’s disease. A culmination of his nearly 40 years of brain research, Gerhardt’s study could help to develop new treatments for the disease.
Study of past South Asian monsoons suggests stronger monsoon rainfall in the future
PROVIDENCE, R.I. [Brown University] — A new study of monsoon rainfall on the Indian subcontinent over the past million years provides vital clues about how the monsoons will respond to future climate change. The study, published in Science Advances ,…
Why scientists want to solve an underground mystery about where microbes live
BU researchers develop first-of-its-kind model to predict which species of soil organisms live in different environments, with huge implications for agriculture, climate change, and public health
Predicting the ocean: Improved forecast and insights for the Mediterranean and Black Seas
Marine forecasters face the challenge of predicting a very complex and constantly changing marine environment by applying ocean science, knowledge and technological skills to produce predictions of the state of the ocean . Operational forecasts are delivered daily in near…
Nutritional supplement proves 92% effective in boosting brain function
An international subject pool was studied to confirm the effectiveness of a whole food complete vitamin and meal replacement product, IQed. The article, co-authored by Lisa Geng; Francine Hamel, EdD, SLP-CCC; Doreen Lewis, Ph.D., appeared in the peer-reviewed journal, Alternative Therapies…
ADHD medications associated with reduced risk of suicidality in certain children
In large observational study, CHOP researchers find ADHD drugs are associated with less suicidal behavior and thoughts in preadolescent children with substantial externalizing behaviors like hyperactivity and oppositional defiance
New form of silicon could enable next-gen electronic and energy devices
Novel crystalline form of silicon could potentially be used to create next-generation electronic and energy devices
Magnetism drives metals to insulators in new experiment
Study provides new tools to probe novel spintronic devices
Adapting laboratory techniques for remote instruction
The COVID-19 pandemic forced instructors to adapt their courses for online learning. Laboratory courses were particularly difficult due to lack of access to specialized equipment for remote learners. To overcome this challenge, researchers from the University of Illinois Urbana-Champaign designed…
Mothers transmitting hepatitis B to children as broken hospital procedures plague Europe
Procedures to prevent the direct transmission of hepatitis B virus (HBV) from mother to child, particularly during and after pregnancy, have significant fragmentation and gaps
Screening reveals coeliac disease cases in children have doubled in 25 years
Mass screening of school age children has led to significantly higher numbers of coeliac disease cases being diagnosed, according to a new study presented today at the 6th World Congress of Paediatric Gastroenterology, Hepatology and Nutrition
Using HPC and experiment, researchers continue to refine graphene production
Researchers from the Technical University of Munich have been using GCS HPC resources to develop more efficient methods for producing graphene at the industrial scale
Researcher gets $2.7 million grant to study seasonal and universal vaccination in aged populations
ATLANTA–Dr. Sang-Moo Kang, professor in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.7 million federal grant to study seasonal and universal vaccination in elderly populations with pre-existing immunity to influenza viruses. The grant from…
Wide variation in cost and transparency of payer-negotiated prices for thyroid cancer care
Study finds up to 70-fold difference in price for some services across peer institutions, even after accounting for factors affecting cost of care delivery
Study finds lower mortality rate for men at high risk for death from prostate cancer who received early postoperative radiation therapy
In a large, international retrospective study, men at high risk for death from prostate cancer had a significant reduction in all-cause mortality if treated with radiation shortly after surgery
Structural uniqueness of the green- and red-light sensing photosensor in cyanobacteria
Overview: Certain cyanobacteria can change the absorbing light colors for photosynthesis using a green- and red-light sensing photosensor protein. A Japanese research group elucidated the molecular structure of RcaE, a representative member of the photosensors. They revealed the unique conformation…
Technique inspired by lace making could someday weave structures in space
Lauren Dreier was paging through a 19th century book by the German architect Gottfried Semper when she spotted some intriguing patterns inspired by lace. A professional artist and designer who often incorporates technology into her work, Dreier, who is also…
Lessons from the last pandemic point the way toward universal flu vaccines
Strong immune responses to unchanging, conserved parts of the 2009 H1N1 pandemic flu virus suggest strategies for effective universal vaccines
Oncotarget: Inflammatory microenvironment & hepatic macrophage in hepatocellular carcinoma
‘The incidence of hepatocellular carcinoma (HCC) is increasing worldwide, and HCC is amongst the leading causes of cancer death globally’
The 8th International Horticulture Research Conference Announcement
To showcase the latest achievements and research progress in the field of horticulture, and promote communication and cooperation among world experts, the 8th International Horticulture Research Conference will be held from July 20 to 22, 2021 in Nanjing, China, and…
Getting they/them pronouns right
Carolina study shows announcing pronouns improves how pronouns are understood
Most US adults may lack knowledge about palliative care
Palliative care can improve outcomes and quality of life for patients with cancer